One-step metal-free construction of fluorescent 5-aryl-2,3-dicyanofurans from simple aryl ketones with DDQ
One-step metal-free construction of fluorescent 5-aryl-2,3-dicyanofurans from simple aryl ketones with DDQ
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DOI：
10.1039/c3ra45462b
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发表时间：
2014
期刊：
影响因子：
3.9
通讯作者：
Jiang‐Sheng Li;F. Cai;Zhi-Wei Li;Weidong Liu;J. Simpson;Yuan Xue;Huai‐Lin Pang;Peng-mian Huang;Zhong Cao;Dao-Lin Li
中科院分区：
文献类型：
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作者：
Jiang‐Sheng Li;F. Cai;Zhi-Wei Li;Weidong Liu;J. Simpson;Yuan Xue;Huai‐Lin Pang;Peng-mian Huang;Zhong Cao;Dao-Lin Li
用DDQ处理富电子芳基酮，合成了一系列具有荧光的5-芳基-2，3-二氰基呋喃。底物中苯环上烷氧基取代基的存在对于有效的环化反应至关重要。这种新的方法允许从简单的芳基酮中无金属地构建呋喃环。
A variety of fluorescent 5-aryl-2,3-dicyanofurans were prepared by the treatment of electron-rich aryl ketones with DDQ. The presence of an alkoxy substituent on the benzene ring in the substrates was essential for an efficient cyclization to occur. This novel approach allows the metal-free construction of furan rings from simple aryl ketones.