DIRECT REGIONAL ASSIGNMENT OF THE GENE FOR VITAMIN-D BINDING-PROTEIN (GC-GLOBULIN) TO HUMAN-CHROMOSOME 4Q11-Q13 AND IDENTIFICATION OF AN ASSOCIATED DNA POLYMORPHISM
DIRECT REGIONAL ASSIGNMENT OF THE GENE FOR VITAMIN-D BINDING-PROTEIN (GC-GLOBULIN) TO HUMAN-CHROMOSOME 4Q11-Q13 AND IDENTIFICATION OF AN ASSOCIATED DNA POLYMORPHISM
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DOI：
10.1007/bf00401232
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发表时间：
1986-07-01
期刊：
影响因子：
5.3
通讯作者：
GEORGE, DL
中科院分区：
文献类型：
--
作者：
COOKE, NE;WILLARD, HF;GEORGE, DL
Using a characterized human vitamin D binding protein (DBP) cDNA probe and a panel of rodent X human somatic cell hybrids, we established the chromosomal location of the structural gene for DBP on human chromosome 4. In situ hybridization of 3H-labeled DBP cDNA to human metaphase chromosomes confirmed this assignment and allowed regional localization to bands 4q11-4q13. A restriction fragment length polymorphism associated with the DBP gene that should prove useful in future linkage studies was identified with the enzyme BamHI.
