New efficient iterative approaches to polycyclic ethers.
New efficient iterative approaches to polycyclic ethers.
复制标题
多环醚的新有效迭代方法。
作者：
F. P. Marmsaeter;F. West
海洋聚醚阶梯毒素的壮观结构激发了合成化学家开发出许多巧妙的方法来组装这些复杂的骨架。一个有趣的策略是使用短而可靠的反应序列，以迭代的方式构建连续的环。理想的方法应该能够容忍环尺寸的变化和桥头堡位置的替换。本文概述了这一领域的最新进展。
The imposing structures of the marine polyether ladder toxins have inspired synthetic chemists to develop many clever methods for assembling these complex skeletons. One intriguing strategy is to use a short and reliable sequence of reactions to build successive rings in an iterative fashion. The ideal approach should tolerate variation in ring size and substitution at the bridgehead positions. This paper offers an overview of recent progress in this field.