High occurrence rate of glaucoma among patients with Alzheimer's disease
High occurrence rate of glaucoma among patients with Alzheimer's disease
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DOI：
10.1159/000047976
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发表时间：
2002-01-01
影响因子：
2.4
通讯作者：
Erb, C
中科院分区：
文献类型：
--
作者：
Bayer, AU;Ferrari, F;Erb, C
本研究的目的是揭示阿尔茨海默病（AD）患者青光眼的发生率。德国上巴伐利亚州四家疗养院的所有112例符合可能AD诊断标准的患者均纳入本研究。在112例AD患者中，29例（25.9%）发现视野缺损和/或视盘杯状与青光眼诊断相符。与对照组（5.2%）和西方国家青光眼患病率（2.6-4.7%）相比，AD患者的青光眼发生率可能显著增加。此外，在AD患者中未发现视野和视乳头正常的高眼压。对照组的高眼压患病率为7.8%，与之前的调查结果相似。因此，我们假设AD患者的视神经似乎对升高的眼内压水平的抵抗力较低。版权所有（C）2002 S. Karger AG，巴塞尔。
The purpose of the current study was to reveal the occurrence rate of glaucoma among patients with Alzheimer's disease (AD). All 112 patients of four nursing homes in Upper Bavaria, Germany, who met the diagnostic criteria of probable AD, were incorporated into the study. Visual field defects and/or optic disc cupping compatible with the diagnosis of glaucoma were found in 29 out of 112 patients with AD (25.9%). When compared to a control group (5.2%) and to the prevalence of glaucoma in western countries revealed in a number of glaucoma surveys (2.6-4.7%), patients with AD may have a significantly increased occurrence rate of glaucoma. In addition, ocular hypertension with normal visual fields and normal optic nerve heads was not found in patients with AD. The prevalence of ocular hypertension in the control group was 7.8% and parallels previous surveys. Therefore, we assume that the optic nerve seems to be less resistant to elevated intraocular pressure levels in AD patients. Copyright (C) 2002 S. Karger AG, Basel.