P1 gene of Mycoplasma pneumoniae isolated from 2016 to 2019 and relationship between genotyping and macrolide resistance in Hokkaido, Japan
P1 gene of Mycoplasma pneumoniae isolated from 2016 to 2019 and relationship between genotyping and macrolide resistance in Hokkaido, Japan
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DOI：
10.1099/jmm.0.001365
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发表时间：
2021-01-01
影响因子：
3
通讯作者：
Manabe, Atsushi
中科院分区：
文献类型：
--
作者：
Ishiguro, Nobuhisa;Sato, Rikako;Manabe, Atsushi
我们对北海道的515个肺炎支原体标本进行了鉴定。2013年和2014年，p1基因1型菌株占主导地位，对大环内酯类药物的耐药性超过50%。2017年后，以大环内酯类药物敏感为主的p1基因2型谱系增多，大环内酯类药物耐药性患病率2017年为31.0%，2018年为5.3%，2019年为16.3%。
We characterized 515 Mycoplasma pneumoniae specimens in Hokkaido. In 2013 and 2014, the p1 gene type 1 strain, mostly macrolide-resistant, was dominant and the prevalence of macrolide resistance was over 50 %. After 2017, the p1 gene type 2 lineage, mostly macrolide-sensitive, increased and the prevalence of macrolide resistance became 31.0 % in 2017, 5.3 % in 2018 and 16.3 % in 2019.