Septic shock without documented infection: an uncommon entity with a high mortality

Septic shock without documented infection: an uncommon entity with a high mortality
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无感染记录的感染性休克:一种死亡率很高的罕见疾病

DOI:
10.1007/s001340051055
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发表时间:
1999
影响因子:
38.9
通讯作者:
J. Vincent
J. Vincent
中科院分区:
医学1区
文献类型:
--
作者:
Walter Reyes;Serge Brimioulle;J. Vincent

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目的:确定临床确诊感染的患者是否与明显脓毒症但无明确感染源的患者有相同的结局。设计:回顾性分析患者资料。患者:所有在31张病床的重症监护室(ICU)接受脓毒性休克治疗的患者。87%的人有临床确定的感染源。无临床明确感染源的感染性休克患者的ICU死亡率高于有临床明确感染源的患者(86%vs66%,p < 0.05)。结论:少数感染性休克患者无临床明确感染。这些患者的死亡率高于已确定感染的患者。
Objectives: To determine whether patients with clinically identified infection have the same outcome as patients with apparent sepsis but no identified infectious source.¶Design: Retrospective analysis of patient data.¶Patients: All patients treated with septic shock in a 31-bed intensive care unit (ICU) over a 3-year period.¶Results: Data from 227 patients were analysed. Eighty-seven percent had a clinically identified source of infection. ICU mortality was higher in septic shock patients without a clinically identified source of infection than in those with an identified source of infection (86 % versus 66 %, p < 0.05).¶Conclusions: A small number of patients presenting with septic shock have no clinically identified infection. These patients have a higher mortality rate than patients in whom an infection is identified.
DOI: 10.1056/nejm199007263230405
发表时间: 1990-07-26
影响因子: 158.5
作者:
LEVINE, B;KALMAN, J;PACKER, M
通讯作者: PACKER, M