MRI measurement of the hemodynamics of the pulmonary and systemic arterial circulation: Influence of breathing maneuvers
MRI measurement of the hemodynamics of the pulmonary and systemic arterial circulation: Influence of breathing maneuvers
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DOI：
10.2214/ajr.04.1738
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发表时间：
2006-08-01
影响因子：
5
通讯作者：
Kauczor, Hans-Ulrich
中科院分区：
文献类型：
--
作者：
Ley, Sebastian;Fink, Christian;Kauczor, Hans-Ulrich
目标。本研究的目的是利用相对比MRI来评估各种呼吸动作对肺循环和全身动脉循环血流动力学的影响。研究对象和方法。25名志愿者接受了相衬MRI检查。在深、大吸气屏气、呼气屏气和平稳呼吸（无屏气）时，测量主动脉、肺动脉干和左右肺动脉的流量。评估的参数包括峰值速度、血流量、速度梯度和加速时间。吸气式屏气和呼气式屏气与不屏气相比，肺血流量和峰值流速显著降低（p < 0.01）。吸气屏气时肺速度梯度显著(p:！0.01)低于呼气屏气组和无屏气组。呼气屏气与不屏气在速度梯度上无差异。无屏气时主动脉峰值流速最低。呼气屏气时速度梯度最大，无屏气时SD最小。吸气屏气、呼气屏气和不屏气在肺动脉干加速时间上无差异。左肺血流分布（45-47%）和右肺血流分布（53-55%）不受呼吸动作的影响。平稳呼吸时的测量显示SD最小。因此，在临床实践中，应考虑无憋气测量来评估血流动力学。
OBJECTIVE. The purpose of this study was to use phase-contrast MRI to evaluate the influence of various breathing maneuvers on the hemodynamics of the pulmonary and systemic arterial circulation.SUBJECTS AND METHODS. Twenty-five volunteers were examined with phase-contrast MRI. Flow measurements were acquired in the aorta, pulmonary trunk, and left and right pulmonary arteries during deep, large-volume inspiratory breath-hold, expiratory breath-hold, and smooth respiration (no breath-hold). Parameters assessed were peak velocity, blood flow, velocity gradient, and acceleration time.RESULTS. Pulmonary blood flow and peak velocity were significantly reduced during inspiratory breath-hold and expiratory breath-hold compared with no breath-hold (p < 0.01). Pulmonary velocity gradient in inspiratory breath-hold was significantly (p:! 0.01) lower than in expiratory breath-hold and no breath-hold. There was no difference in velocity gradient between expiratory breath-hold and no breath-hold. Peak velocity in the aorta was lowest with no breath-hold. Velocity gradient was highest in expiratory breath-hold, and no breath-hold had the smallest SD. Acceleration time in the pulmonary trunk showed no difference between inspiratory breath-hold, expiratory breath-hold, and no breath-hold. Blood flow distribution to the left (45-47%) and to the right (53-55%) lung was not influenced by breathing maneuver.CONCLUSION. Measurements during smooth respiration showed the smallest SD. Therefore, no-breath-hold measurements should be considered for assessment of hemodynamics in clinical practice.