Viruses, immunity, and cancer: Lessons from hepatitis B
Viruses, immunity, and cancer: Lessons from hepatitis B
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DOI：
10.1016/s0002-9440(10)64980-2
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发表时间：
2000-04-01
影响因子：
6
通讯作者：
Chisari, FV
中科院分区：
文献类型：
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作者：
Chisari, FV
从医学院开始，决定病毒感染结果的宿主-病毒相互作用就吸引着我。我第一次积极追求这一兴趣的机会是在我有幸成为美国国立卫生研究院（National Institutes of Health）一个团队的一员时，该团队将乙型肝炎病毒（HBV）传播给了黑猩猩。因此，人们开始对持续的人类病毒感染的免疫生物学产生长期的兴趣，特别是那些感染肝脏的病毒。我非常荣幸这项工作获得了今年的劳-惠普尔奖，让我有机会描述我们目前对这些感染的理解状况。
The host-virus interactions that determine the outcome of viral infections have fascinated me ever since medical school. My first opportunity to actively pursue this interest came when I was lucky enough to be part of a team at the National Institutes of Health that transmitted the hepatitis B virus (HBV) to chimpanzees. 1 Thus began a longstanding interest in the immunobiology of persistent human viral infections, especially those that infect the liver. I am greatly honored that this work has been recognized by the Rous-Whipple Award this year, giving me this opportunity to describe our current state of understanding of these infections.