Use of circulating cathodic antigen strips for the diagnosis of urinary schistosomiasis
Use of circulating cathodic antigen strips for the diagnosis of urinary schistosomiasis
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DOI：
10.1016/j.trstmh.2008.08.018
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发表时间：
2009-01-01
影响因子：
2.2
通讯作者：
van Dam, G. J.
中科院分区：
文献类型：
--
作者：
Midzi, N.;Butterworth, A. E.;van Dam, G. J.
需要快速诊断测试来执行和监测国家血吸虫病控制方案。在津巴布韦农村地区的265名2-19岁学龄前和小学儿童中评价了循环阴极抗原（CCA）尿液试剂条诊断埃及血吸虫感染的现场适用性。用吡喹酮治疗前和治疗后6周，将CCA试纸条与虫卵检测结果进行比较。治疗前患病率（总体为40.4%）和感染强度（由鸡蛋计数确定）随年龄增加而增加。CCA与寄生虫学结果呈显著相关（P
Rapid diagnostic tests are needed for the implementation and monitoring of national schistosomiasis control programmes. The field applicability of the circulating cathodic antigen (CCA) urine reagent strip for the diagnosis of Schistosoma haematobium infection was evaluated among 265 pre- and primary schoolchildren aged 2-19 years in a rural area of Zimbabwe. The CCA strip was compared with egg detection before and six weeks after treatment with praziquantel. Pre-treatment prevalence (overall 40.4%) and intensity of infection, as determined by egg counts, increased with age. CCA and parasitological results were significantly correlated (P