Residue degradation, transfer and risk assessment of pyriproxyfen and its metabolites from tea garden to cup by ultra performance liquid chromatography tandem mass spectrometry
Residue degradation, transfer and risk assessment of pyriproxyfen and its metabolites from tea garden to cup by ultra performance liquid chromatography tandem mass spectrometry
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超高效液相色谱串联质谱法测定吡丙醚及其代谢物从茶园到杯子的残留降解、转移和风险评估
DOI：
10.1002/jsfa.11746
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发表时间：
2022-01-25
影响因子：
4.1
通讯作者：
Zhang, Xinzhong
中科院分区：
文献类型：
--
作者：
Li, Hongxia;Zhong, Qing;Zhang, Xinzhong
背景技术茶是世界上最受欢迎的饮料之一。茶树的生长离不开农药对病虫害的控制。吡丙醚被用作农药替代品来控制茶园中的害虫，但对其残留降解知之甚少。在这里，我们对吡丙醚从茶园到茶杯的降解和代谢进行了综合研究。结果吡丙醚在茶树生长过程中的消散半衰期为2.74 d，产生5种代谢物PYPAC、PYPA、DPH-Pyr、5''-OH-Pyr、4'-OH-Pyr。绿茶和红茶中吡丙醚的总加工因子分别为2.41-2.83和2.77-3.70。吡丙醚及其代谢物的残留量受到不同加工步骤的影响。吡丙醚从绿茶和红茶中浸出到其冲泡液中的总浸出率分别为9.8-12.3%和5.3-13.8%。 5种代谢物的浸出率均高于吡丙醚，增加了摄入风险。结论为保证食用安全，茶叶中吡丙醚推荐最大残留限量值可设定为5 mg·kg(-1)，采前间隔可设定为5 d。 (c) 2022 年化学工业协会。
BACKGROUND Tea is one of the most popular drinks in the world. The growth of tea plant is inseparable from the control of pesticides on diseases and pests. Pyriproxyfen is used as a pesticide substitute to control insect pests in tea gardens, but little is known about its residue degradation. Here, we performed an integrative study of the degradation and metabolism of pyriproxyfen from the tea garden to the cup. RESULTS The dissipation half-life of pyriproxyfen during tea growth was 2.74 days, and five metabolites PYPAC, PYPA, DPH-Pyr, 5 ''-OH-Pyr, and 4 '-OH-Pyr were generated. The total processing factors for pyriproxyfen in green tea and black tea were 2.41-2.83 and 2.77-3.70, respectively. The residues of pyriproxyfen and its metabolites were affected by different processing steps. The total leaching rates of pyriproxyfen from green tea and black tea into their infusions were 9.8-12.3% and 5.3-13.8%, respectively. The leaching rates of the five metabolites were higher than that of pyriproxyfen and increased the intake risk. CONCLUSION To ensure safe consumption, the recommended maximum residue limit value of pyriproxyfen in tea can be set to 5 mg kg(-1) and the pre-harvest interval can be set to 5 days. (c) 2022 Society of Chemical Industry.