Metabolic effects of fasting on human and mouse blood in vivo
Metabolic effects of fasting on human and mouse blood in vivo
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DOI：
10.1080/15548627.2016.1271513
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发表时间：
2017-01-01
期刊：
影响因子：
13.3
通讯作者：
Kroemer, Guido
中科院分区：
文献类型：
--
作者：
Pietrocola, Federico;Demont, Yohann;Kroemer, Guido
饥饿是巨自噬/自噬的强烈生理刺激。在这项研究中，我们解决了是否可以在营养剥夺后测量血细胞自噬的问题。小鼠禁食 48 小时（这会导致体重减轻 20%），或者人类志愿者挨饿长达 4 天（这会导致
Starvation is a strong physiological stimulus of macroautophagy/autophagy. In this study, we addressed the question as to whether it would be possible to measure autophagy in blood cells after nutrient deprivation. Fasting of mice for 48 h (which causes similar to 20% weight loss) or starvation of human volunteers for up to 4 d (which causes