APPLICATION OF POLYMERIC N-ACETYL-D-GLUCOSAMINE (CHITIN) TO VETERINARY PRACTICE
APPLICATION OF POLYMERIC N-ACETYL-D-GLUCOSAMINE (CHITIN) TO VETERINARY PRACTICE
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DOI：
10.1292/jvms.55.743
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发表时间：
1993-10-01
影响因子：
1.2
通讯作者：
TOKURA, S
中科院分区：
文献类型：
--
作者：
OKAMOTO, Y;MINAMI, S;TOKURA, S
将甲壳素制成的海绵状、棉状和片状治疗剂（分别为甲壳素海绵、甲壳素棉和甲壳素片）和甲壳素复合聚酯（NWF）无纺布（甲壳素-NWF）应用于各种类型的创伤、脓肿、手术组织缺损和疝气修补术，共147例临床病例，其中包括72只狗、38头牛、33只猫、2只兔子、1只甲壳素。猴子和一匹马。甲壳素海绵作为手术组织缺损填充剂30例，外伤25例、脓肿31例作为伤口敷料或组织缺损填充剂。 86 例中有 77 例 (89.5%) 愈合良好。 20例因肿瘤切除而将甲壳海绵埋入手术组织缺损中，1例术后1个月肿瘤复发，19例3～24个月未见肿瘤。甲壳素-NWF应用于外伤2例、脓肿12例作为伤口敷料或组织缺损填充剂，6例作为手术组织缺损填充剂，12例脐疝作为疝环缝合处假体。 32 例中有 28 例（87.5%）愈合良好。应用甲壳棉作为伤口敷料或组织缺损填充剂治疗8例外伤和12例脓肿。 20 例中有 18 例 (90.0%) 愈合良好。甲壳素片作为伤口敷料或组织缺损填充剂应用于创伤9例。 9 例中有 8 例 (88.9%) 愈合良好。在所有情况下，均未观察到副作用。
The sponge-, cotton-, and flake-type remedies made of chitin (chitin-sponge, chitin-cotton, and chitin-flake, respectively), and non-woven fabric of polyester (NWF) composited with chitin (chitin-NWF) were applied to various types of trauma, abscess, surgical tissue defect and herniorrhaphy in 147 clinical cases including 72 dogs, 38 cows, 33 cats, 2 rabbits, one monkey and one horse. Chitin-sponge was applied in 30 cases as filling agent of surgical tissue defect, and in 25 cases of trauma, 31 cases of abscess as wound dressing or tissue defect filling agent. In 77 out of 86 cases (89.5%), good healing developed. When chitin-sponge was buried in surgical tissue defects due to oncotomy in 20 cases, recurrence of the tumor developed in one case on one month post-operatively, but wag not recognized for 3-24 months in 19 cases. Chitin-NWF was applied in 2 cases of trauma and 12 cases of abscess as wound dressing or tissue defect filling agent, 6 cases as filling agent of surgical tissue defect, and 12 cases of umbilical hernia as prosthesis of suture site of hernia ring. In 28 out of 32 cases (87.5%), good healing developed. Chitin-cotton was applied in 8 cases of trauma and 12 cases of abscess as wound dressing or tissue defect filling agent. In 18 out of 20 cases (90.0%), good healing developed. Chitin-flake was applied in 9 cases of trauma as wound dressing or tissue defect filling agent. In 8 out of 9 cases (88.9%), good healing developed. In all cases, no side effects were observed.