The microbiota of early periodontitis lesions in adults.
The microbiota of early periodontitis lesions in adults.
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成人早期牙周炎病变的微生物群。
DOI：
10.1111/j.1600-051x.1989.tb01676.x
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发表时间：
1989
影响因子：
6.7
通讯作者：
Bouldin,H
中科院分区：
文献类型：
--
作者：
Tanner,A;Bouldin,H
比较了4名成人(29-40岁)浅表进行性(活动性)牙周病变的优势可培养微生物区系与浅表非活动性部位的可培养微生物区系。牙周附着水平被纵向监测，在前1-2个月内附着丧失2-3 mm的部位被认为是疾病活动期。非活跃站点的依恋水平没有变化。浅层土壤微生物区系以革兰氏阴性杆菌为主，其中直肠Wolinella recta为优势菌种。、福赛斯拟杆菌和核梭杆菌。与非活动部位相比，直肠假丝酵母菌在活跃部位的发生率和比例更高，且与探查出血呈正相关。对从各个地点分离的物种的聚类分析将每个个体的地点分组在一起。这项初步调查表明，与先前报道的晚期牙周炎部位的病原体类似，成人早期牙周炎可能与病原体的范围类似，不同的受试者可能表现出不同的牙周感染。
The predominant cultivable microbiota of shallow progressive (active) periodontal lesions in 4 adults (29–40 years) was compared to that of shallow inactive sites. Periodontal attachment levels were monitored longitudinally, and sites showing 2–3 mm attachment loss in the previous 1–2 months were considered disease active. Inactive sites showed no change in attachment level. The microbiota of shallow sites was dominated by gram negative rod species including Wolinella recta. Bacteroides forsythus, and Fusobacterium nucleatum. W. recta was isolated in higher incidence and proportions from the active compared to inactive sites, and showed a positive relationship to bleeding on probing. Cluster analysis of species isolated from sites grouped sites from each individual together. This preliminary investigation suggested that a similar range of pathogens may be related to early periodontitis in adults as that previously reported for advanced diseased sites, and that different subjects may demonstrate different periodontal infections.