Implications of Three-Step Swimming Patterns in Bacterial Chemotaxis
Implications of Three-Step Swimming Patterns in Bacterial Chemotaxis
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DOI：
10.1016/j.bpj.2010.11.029
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发表时间：
2011-01-05
影响因子：
3.4
通讯作者：
Wu, Xiao-Lun
中科院分区：
文献类型：
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作者：
Altindal, Tuba;Xie, Li;Wu, Xiao-Lun
我们最近发现，海洋细菌溶藻弧菌执行一个循环的三步（运行反向轻弹）运动模式，这是显着不同的两步（运行翻滚）模式的大肠杆菌。据我们所知，这种新颖的游泳模式是如何被溶藻弧菌的细胞调节的目前尚不清楚，但其对细菌趋化性的意义是不言而喻的，并将在本文中描述。使用统计方法，我们计算了细胞在线性化学梯度中执行三步模式的迁移速度，并发现自然产生双相趋化反应。这种反应对细胞适应海洋环境的意义及其与E。大肠杆菌的反应进行了讨论。
We recently found that marine bacteria Vibrio alginolyticus execute a cyclic three-step (run-reverse-flick) motility pattern that is distinctively different from the two-step (run-tumble) pattern of Escherichia coli. How this novel, to our knowledge, swimming pattern is regulated by cells of V. alginolyticus is not currently known, but its significance for bacterial chemotaxis is self-evident and will be delineated herein. Using a statistical approach, we calculated the migration speed of a cell executing the three-step pattern in a linear chemical gradient, and found that a biphasic chemotactic response arises naturally. The implication of such a response for the cells to adapt to ocean environments and its possible connection to E. coli's response are also discussed.