OneDep: Unified wwPDB System for Deposition, Biocuration, and Validation of Macromolecular Structures in the PDB Archive.
OneDep: Unified wwPDB System for Deposition, Biocuration, and Validation of Macromolecular Structures in the PDB Archive.
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DOI：
10.1016/j.str.2017.01.004
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发表时间：
2017-03-07
期刊：
影响因子：
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通讯作者：
Burley SK
中科院分区：
文献类型：
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作者：
Young JY;Westbrook JD;Feng Z;Sala R;Peisach E;Oldfield TJ;Sen S;Gutmanas A;Armstrong DR;Berrisford JM;Chen L;Chen M;Di Costanzo L;Dimitropoulos D;Gao G;Ghosh S;Gore S;Guranovic V;Hendrickx PMS;Hudson BP;Igarashi R;Ikegawa Y;Kobayashi N;Lawson CL;Liang Y;Mading S;Mak L;Mir MS;Mukhopadhyay A;Patwardhan A;Persikova I;Rinaldi L;Sanz-Garcia E;Sekharan MR;Shao C;Swaminathan GJ;Tan L;Ulrich EL;van Ginkel G;Yamashita R;Yang H;Zhuravleva MA;Quesada M;Kleywegt GJ;Berman HM;Markley JL;Nakamura H;Velankar S;Burley SK
OneDep是一个统一的系统，用于将实验确定的生物大分子结构沉积、生物固化和验证到蛋白质数据库（PDB）存档中，由全球蛋白质数据库（wwPDB）合作伙伴开发。这一新系统旨在确保wwPDB能够满足科学界在未来几十年不断变化的存档要求。OneDep统一了所有wwPDB、EMDB和BMRB沉积站点的沉积、生物固化和验证管道，更注重这些存档中的数据质量和完整性，同时支持沉积数量的增长以及平均大小和复杂性的增加。在本文中，我们描述了OneDep系统的设计，功能操作和支持基础设施，并提供初步的性能评估。
OneDep, a unified system for deposition, biocuration, and validation of experimentally determined structures of biological macromolecules to the Protein Data Bank (PDB) archive, has been developed as a global collaboration by the Worldwide Protein Data Bank (wwPDB) partners. This new system was designed to ensure that the wwPDB could meet the evolving archiving requirements of the scientific community over the coming decades. OneDep unifies deposition, biocuration, and validation pipelines across all wwPDB, EMDB, and BMRB deposition sites with improved focus on data quality and completeness in these archives, while supporting growth in the number of depositions and increases in their average size and complexity. In this paper, we describe the design, functional operation, and supporting infrastructure of the OneDep system, and provide initial performance assessments.