Factors affecting the pregnancy rate after microsurgical reversal of tubal ligation

Factors affecting the pregnancy rate after microsurgical reversal of tubal ligation
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DOI:
10.1016/s0015-0282(03)00661-7
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发表时间:
2003-08-01
影响因子:
6.7
通讯作者:
Hanafi, MM
Hanafi, MM
中科院分区:
医学2区
文献类型:
--
作者:
Hanafi, MM

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Objective: To evaluate the factors affecting the pregnancy rate after microsurgical reversal of tubal ligation.Design: Retrospective clinical study.Setting: Private practice affiliated with a tertiary care center.Patient(s): One hundred twenty-eight consecutive patients who underwent tubal reversal between October 1992 and May 2001.Intervention(s): Microsurgical tubal reanastomosis performed by a single surgeon.Main Outcome Measure(s): Subsequent pregnancy rates were evaluated with Fisher's exact tests and logistic regression according to clinical characteristics of patients.Result(s): The pregnancy rate was 85.7% (54 out of 63) in patients less than or equal to35 years of age vs. 45.5% (10 out of 22) in patients >35 years. The odds ratio (OR) between the two age groups was 7.20, with a 95% confidence interval (CI) of 2.41 to 21.55. The pregnancy rate was 85.4% (35 out of 41) in patients with body mass index (BMI) less than or equal to25 compared with 65.9% (29 out of 44) in patients with BMI >25 (OR 3.02; CI 1.04 to 8.77). Patients sterilized : 8 years had a pregnancy rate of 87.2% (34 out of 39), vs. 65.2% (30 out of 46) in patients sterilized >8 years (OR 3.63; CI 1.19 to 11.09).Conclusion(s): Age was the primary statistically significant factor affecting pregnancy rate in tubal reversal patients. Body mass index and duration of sterilization had smaller, but statistically significant, associations with pregnancy rate. (C) 2003 by American Society for Reproductive Medicine.