GOLGI STUDY OF NEURONAL TYPES IN NEOSTRIATUM OF MONKEYS
GOLGI STUDY OF NEURONAL TYPES IN NEOSTRIATUM OF MONKEYS
复制标题
DOI：
10.1016/0006-8993(76)90669-7
复制
发表时间：
1976-01-01
期刊：
影响因子：
2.9
通讯作者：
PASIK, T
中科院分区：
文献类型：
--
作者：
DIFIGLIA, M;PASIK, P;PASIK, T
对猕猴[Macaca mulatta和M.通过Golgi-Kopsch灌注方法制备的[食蟹猴]显示存在至少6种神经元类型。多刺I型是中等大小，具有高密度的树突棘。轴突延伸远远超出树突领域，并发出许多侧支。多刺型II是中型或大型，具有长而厚的树突，棘密度相对较低，轴突与前一型相似，但侧支较少。多刺型I为中等大小，在索马体附近有静脉曲张的树突和树枝状的细轴突。第二型棘状突起较大，有许多粗细不等的静脉树突。第三型棘状突起为中等大小，树突光滑，在树突区域内有大量的轴突分支。神经胶质细胞小，有许多分支过程。新纹状体有2种不同类型的长轴突多刺神经元（多刺I和II），其中一些可能有助于传出系统。典型的高尔基体II型细胞也有2种（刺状I和III）或多达4种（刺状I、II、III和神经胶质样）。大的神经元属于2个独立的群体，一个具有树突棘和长轴突（大版本的spiny II），另一个具有varicostieis，可能是短轴突（aspiny II）。对新纹状体神经生理学数据的现实解释必须考虑到所有细胞类型，而不是将其视为具有少量输出细胞的中间神经元池的当前观点。
Examination of the neostriatum of monkeys [Macaca mulatta and M. cynomolgus] prepared by the Golgi-Kopsch perfusion method revealed the presence of at least 6 neuronal types. The spiny type I is medium size with a high density of dendritic spines. The axon extends well beyond the dendritic field and gives off many collaterals. The spiny type II is either medium or large size, has long thick dendrites with a relatively low density of spines and an axon similar to that of the previous type but with fewer collaterals. The aspiny type I is medium size and varicose dendrites and a thin axon arborizing in the immediate vicinity of the soma. The aspiny type II is large, with many thick and thin varicose dendrites. The aspiny type III is medium size with smooth dendrites and an axon ramifying profusely within the dendritic field. The neurogliform cell is small with many branching processes. The neostriatum has 2 distinct types of spiny neurons with long axons (spiny I and II), some of which may contribute to the efferent systems. There are also 2 (aspiny I and III) or perhaps as many as 4 categories (aspiny I, II, III and neurogliform) of typical Golgi type II cells. Large neurons belong to 2 separate populations, one with dendritic spines and a long axon (large version of spiny II), and one with varicostieis and presumably a short axon (aspiny II). A realistic interpretation of neurophysiologic data on the neostriatum must take into account all cell types instead of the current view of considering it as a pool of interneurons with few output cells.