The physiological response to Trier Social Stress Test relates to subjective measures of stress during but not before or after the test
The physiological response to Trier Social Stress Test relates to subjective measures of stress during but not before or after the test
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DOI：
10.1016/j.psyneuen.2011.05.012
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发表时间：
2012-01-01
影响因子：
3.7
通讯作者：
Schubert, Melanie
中科院分区：
文献类型：
--
作者：
Hellhammer, Juliane;Schubert, Melanie
特里尔社会压力测试（Trier Social Stress Test，TSST）是一种有效的心理社会实验室方案，用于诱导人类压力，并已用于许多研究。应激导致下丘脑垂体肾上腺轴（HPAA）和自主神经系统（ANS）的生理反应。常见的生物标志物是皮质醇水平和心率。除了生理应激反应外，TSST还引发心理反应，如感知压力，焦虑和情绪不安全感的增加。而HPA和ANS措施可以很容易地获得TSST期间本身，心理措施通常是确定之前（基线）和之后的TSST。这可能会排除压力事件本身的信息。在本研究中，我们评估了知觉压力，焦虑和情绪不安全感之前，期间和之后的TSST使用视觉模拟量表。此外，还评估了皮质醇水平和心率。260名年龄在16-60岁的健康非吸烟男性的数据用于分析。我们的研究结果表明，压力感知，焦虑和情绪不安全感显着较高的TSST期间相比，后TSST评级。此外，我们的研究结果表明，在TSST和生理应激反应（皮质醇和心率）的压力感知的心理应激反应的协方差，虽然解释的方差很小。这一观察结果没有发现前和后TSST评级表明，评估心理压力的措施，在压力源本身提出了一个更翔实的措施的压力反应。(C)2011爱思唯尔有限公司保留所有权利。
The Trier Social Stress Test (TSST) is an effective psychosocial laboratory protocol for inducing stress in humans and has been used in numerous research studies. The stressor leads to a physiological response of the hypothalamus pituitary adrenal axis (HPAA) and the autonomous nervous system (ANS). Common biomarkers are cortisol levels and heart rate. In addition to the physiological stress response, the TSST also triggers a psychological response such as an increase in perceived stress, anxiety and emotional insecurity. Whereas HPA and ANS measures can easily be obtained for the TSST period itself, psychological measures are usually determined prior to (baseline) and after the TSST. This may exclude information of the stressful event itself. In the present study, we assessed perceived stress, anxiety and emotional insecurity before, during and after the TSST using visual analogue scales. In addition, cortisol levels and heart rates were assessed. Data of 260 healthy non-smoking males aged 16-60 yrs were used for analyses. Our results show that stress perception, anxiety and emotional insecurity were significantly higher during the TSST as compared to post-TSST ratings. Furthermore, our results suggest a covariance of the psychological stress response during the TSST and the physiological stress responses (cortisol and heart rate) for stress perception though the explained variance was small. This observation was not found for pre- and post-TSST ratings suggesting that assessing psychological stress measures during the stressor itself present a more informative measure of the stress response. (C) 2011 Elsevier Ltd. All rights reserved.