Hypopharyngeal cancer patient care evaluation

Hypopharyngeal cancer patient care evaluation
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DOI:
10.1097/00005537-199708000-00001
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发表时间:
1997-08-01
期刊:
影响因子:
2.6
通讯作者:
Fremgen, AM
Fremgen, AM
中科院分区:
医学2区
文献类型:
--
作者:
Hoffman, HT;Karnell, LH;Fremgen, AM

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在美国进行了一项调查,以确定下咽鳞状细胞癌治疗的人口统计学和护理标准。数据来自769家医院的自愿提交的癌症登记和病历信息,这些医院代表了1980-1985年和1990-1992年间诊断的2939例病例。临床结果,采用的诊断程序,治疗实践,并提出了结果。总体而言,5年疾病特异性生存率为33.4%,分别为63.1%(I期)、57.5%(II期)、41.8%(III期)和22%(IV期)。单纯手术治疗的存活率最高(50.4%),手术加放疗的存活率与单纯手术治疗相似(48%),单纯放疗者的存活率较差(25.8%)。这一分析提供了一个标准,可以将当前的治疗实践与未来的临床试验进行比较。
A survey was conducted to identify demographics and standards of care for treatment of hypopharyngeal squamous cell carcinoma in the United States. Data were accrued from voluntary submission of cancer registry and medical chart information from 769 hospitals representing 2939 cases diagnosed from 1980 to 1985 and 1990 to 1992. Clinical findings, diagnostic procedures employed, treatment practices, and outcome are presented. Overall, 5-year disease-specific survival was 33.4%, which segregated to 63.1% (stage I), 57.5% (stage II), 41.8% (stage III), and 22% (stage IV). Survival was best for patients treated with surgery only (50.4%), similar with combined surgery and irradiation (48%), and worse with irradiation only (25.8%). This analysis provides a standard to which current treatment practice and future clinical trials may be compared.