Biospecimen Reporting for Improved Study Quality (BRISQ)
Biospecimen Reporting for Improved Study Quality (BRISQ)
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DOI：
10.1002/cncy.20147
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发表时间：
2011-04-25
影响因子：
3.4
通讯作者：
Vaught, Jim
中科院分区：
文献类型：
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作者：
Moore, Helen M.;Kelly, Andrea B.;Vaught, Jim
人类生物标本的采集、处理和储存可能会显著改变其分子组成和一致性。这些生物样本预分析因素，反过来，影响实验结果和重现科学结果的能力。目前，科学出版物和法规提交资料中报告的生物标本分析前条件特定信息的范围和类型差异很大。为了提高使用人体组织的研究质量，以全面、准确和标准化的方式报告生物标本处理信息至关重要。本文概述的生物标本报告以提高研究质量（BRISQ）建议适用于使用人类生物标本的任何研究。报告这些细节的目的是为从研究人员到监管机构的其他人提供更一致和标准化的信息，以更好地评估，解释，比较和重现实验结果。BRISQ指南被提议作为一个重要和及时的资源工具，以加强生物制药相关研究的沟通和出版，并帮助向患者贡献者和倡导团体保证他们的贡献受到重视和尊重。癌症（癌症细胞病理学）2011;119：92-101。2011年由美国癌症协会出版。
Human biospecimens are subjected to collection, processing, and storage that can significantly alter their molecular composition and consistency. These biospecimen preanalytical factors, in turn, influence experimental outcomes and the ability to reproduce scientific results. Currently, the extent and type of information specific to the biospecimen preanalytical conditions reported in scientific publications and regulatory submissions varies widely. To improve the quality of research that uses human tissues, it is crucial that information on the handling of biospecimens be reported in a thorough, accurate, and standardized manner. The Biospecimen Reporting for Improved Study Quality (BRISQ) recommendations outlined herein are intended to apply to any study in which human biospecimens are used. The purpose of reporting these details is to supply others, from researchers to regulators, with more consistent and standardized information to better evaluate, interpret, compare, and reproduce the experimental results. The BRISQ guidelines are proposed as an important and timely resource tool to strengthen communication and publications on biospecimen-related research and to help reassure patient contributors and the advocacy community that their contributions are valued and respected. Cancer (Cancer Cytopathol) 2011;119:92-101. Published 2011 by the American Cancer Society.*