Cartilage thickness measurements from optical coherence tomography.
Cartilage thickness measurements from optical coherence tomography.
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DOI：
10.1364/josaa.20.000357
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发表时间：
2003-02
期刊：
影响因子：
--
通讯作者：
J. Rogowska;C. M. Bryant;M. Brezinski
中科院分区：
文献类型：
--
作者：
J. Rogowska;C. M. Bryant;M. Brezinski
提出了一种新的半自动图像处理方法，用于光学相干断层扫描（OCT）中软骨边界的检测。特别是，我们专注于兔软骨，因为这是测试软骨保护剂和软骨修复技术的重要动物模型。本文提出的新的边界检测系统包括：（1）用于图像增强和散斑抑制的自适应滤波技术，（2）边缘检测，和（3）通过图搜索的边缘连接。该过程需要几个步骤，并且可以自动化。OCT图像上软骨厚度的定量测量值与组织学测量值相关性良好。
We describe a new semiautomatic image processing method for detecting the cartilage boundaries in optical coherence tomography (OCT). In particular, we focus on rabbit cartilage since this is an important animal model for testing both chondroprotective agents and cartilage repair techniques. The novel boundary-detection system presented here consists of (1) an adaptive filtering technique for image enhancement and speckle reduction, (2) edge detection, and (3) edge linking by graph searching. The procedure requires several steps and can be automated. The quantitative measurements of cartilage thickness on OCT images correlated well with measurements from histology.