The hypotensive response to des-Arg9-bradykinin increases during E. coli septicemia in the pig.
The hypotensive response to des-Arg9-bradykinin increases during E. coli septicemia in the pig.
复制标题
在猪的大肠杆菌败血症期间,对 des-Arg9-缓激肽的低血压反应增加。
DOI:
10.1007/978-1-4615-9546-5_64
复制
发表时间:
1989
影响因子:
--
通讯作者:
Hans Fritz
中科院分区:
文献类型:
--
作者:
Matthias Siebeck;Eric T. Whalley;Hans Hoffmann;Joachim Weipert;Hans Fritz
The sensitivity to des-Arg9-bradykinin of the cardiovascular system was largely increased in piglets with E. coli bacteremia. However, the sensitivity to bradykinin was unchanged under the same condition. These findings indicate the appearance of the kinin B1-receptor in the systemic circulation of the pig during septicemia. Bradykinin induced responses suggest a stable effect mediated by the classical B2-receptor.