HIV Serostatus Disclosure Among Men Who Have Sex with Men in China in the Era of U=U and PrEP.
HIV Serostatus Disclosure Among Men Who Have Sex with Men in China in the Era of U=U and PrEP.
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U=U和PrEP时代中国男男性行为者HIV血清状况披露
DOI：
10.1007/s10461-021-03502-7
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发表时间：
2022-05
影响因子：
4.4
通讯作者：
Ekstrom, Anna Mia
中科院分区：
文献类型：
--
作者：
Cao, Wangnan;Li, Jinghua;Sun, Shengzhi;Sturm, Carla;Peng, Liping;Gu, Jing;Hao, Chun;Hou, Fengsu;Wei, Dannuo;You, Xinyi;Deng, Yang;Ekstrom, Anna Mia
关键词：
鉴于近期关于“检测不到病毒=不具有传染性”（U = U）以及暴露前预防（PrEP）的相关证据，本研究旨在调查中国男男性行为者（MSM）的艾滋病病毒（HIV）告知行为及其与性风险行为、U = U和PrEP知晓情况之间的关联。2018年至2019年，通过位于中国成都的一个对同性恋友好的非政府组织招募了689名男男性行为者进行横断面调查。通过结构化的自填问卷收集信息。纳入的样本包括554名（80.4%）HIV阴性参与者和135名（19.6%）HIV感染状况不明的参与者。在告知方面，41.4%的参与者总是向所有性伴侣告知自己的HIV感染状况（告知行为），而30.4%的参与者总是询问所有性伴侣的HIV感染状况（询问行为）。只有五分之一的人了解U = U，但这与告知行为或询问行为均无统计学关联。一半（50.5%）的人听说过PrEP，但这与告知行为或询问行为也均无统计学关联。告知和询问行为的常见障碍包括对HIV感染的风险认知较低、有性传播感染病史、有接受性性行为以及有与临时性伴侣发生性行为的历史。我们发现，在中国男男性行为者的这项研究中，U = U和PrEP的知晓率以及HIV血清学状态告知都较低，且两者之间没有关联。这些数据表明中国男男性行为者之间存在巨大的信息差距。
Given the recent evidence on “Undetectable = Untransmittable” (U=U) and pre-exposure prophylaxis (PrEP), the present study aimed to investigate HIV disclosure behaviors and their associations with sexual risk behaviors and U=U and PrEP awareness among men who have sex with men (MSM) in China. A cross-sectional survey was conducted among 689 MSM recruited through a gay-friendly non-governmental organization located in Chengdu, China in 2018–2019. Information was collected by a structured self-administrated questionnaire. The enrolled sample included 554 (80.4%) participants who were HIV-negative and 135 (19.6%) participants with an unknown HIV status. In terms of disclosure, 41.4% of participants informed all partners about their HIV status all the time (informing behavior), while 30.4% asked all partners about their HIV status all the time (asking behavior). Only one-fifth knew about U=U, but this was not statistically associated with either informing or asking behavior. Half (50.5%) had heard of PrEP but this was not statistically associated with either informing or asking behavior. Common barriers to informing and asking behaviors were lower risk perception of HIV infection, a history of sexually transmitted infections, engagement in receptive sex, and a history of sex with casual partners. We found that both U=U and PrEP awareness and HIV serostatus disclosure were infrequent and not associated in this study of Chinese MSM. These data indicate huge information gaps among MSM in China.
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影响因子：
4.6
作者：
Deuba, Keshab;Sapkota, Diksha;Ekstrom, Anna Mia
通讯作者：
Ekstrom, Anna Mia
影响因子：
1.7
作者：
Przybyla SM;Golin CE;Widman L;Grodensky CA;Earp JA;Suchindran C
通讯作者：
Suchindran C
影响因子：
12.7
作者：
Eaton LA;Kalichman SC;Cherry C
通讯作者：
Cherry C
影响因子：
4.5
作者：
Marcus U;Gassowski M;Drewes J
通讯作者：
Drewes J
DOI：
10.1056/nejmoa1600693
发表时间：
2016-09-01
期刊：
The New England journal of medicine
影响因子：
--
作者：
Cohen MS;Chen YQ;McCauley M;Gamble T;Hosseinipour MC;Kumarasamy N;Hakim JG;Kumwenda J;Grinsztejn B;Pilotto JH;Godbole SV;Chariyalertsak S;Santos BR;Mayer KH;Hoffman IF;Eshleman SH;Piwowar-Manning E;Cottle L;Zhang XC;Makhema J;Mills LA;Panchia R;Faesen S;Eron J;Gallant J;Havlir D;Swindells S;Elharrar V;Burns D;Taha TE;Nielsen-Saines K;Celentano DD;Essex M;Hudelson SE;Redd AD;Fleming TR;HPTN 052 Study Team
通讯作者：
HPTN 052 Study Team