Persistent CT nephrograms following cardiac catheterisation and intervention: initial observations.
Persistent CT nephrograms following cardiac catheterisation and intervention: initial observations.
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DOI：
10.1007/s13244-011-0131-2
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发表时间：
2012-02
影响因子：
4.7
通讯作者：
Li, Chin-Shang
中科院分区：
文献类型：
--
作者：
Katzberg, Richard W;Monsky, Wayne L;Prionas, Nicolas D;Sidhar, Vishal;Southard, Jeffrey;Carlson, Janine;Boone, John M;Lin, Tzu-Chun;Li, Chin-Shang
目的描述心导管插管和干预后24小时无增强肾CT检测到的持续性肾图像。本前瞻性研究符合《健康保险流通与责任法案》，并经机构审查委员会批准。29名患者（20名男性，9名女性，平均年龄63.27岁，年龄范围41-85岁）同意在心导管置入术后24小时接受肾脏非增强双能计算机断层扫描（CT）。CT衰减值（Hounsfield单位）来自皮质和髓质区域，并测量单肾总实质碘值（毫克）。统计采用Spearman等级相关系数和双侧Fisher精确检验。10/29（34%）的患者至少有一个肾脏出现局灶性肾图（范围，每个肾脏1 - 5个区域），13/29（45%）的患者出现双侧全肾图。局灶性肾图与心导管透视时间相关（r = 0.48; P = 0.0087）。对于全肾图，左右肾总碘含量与透视时间（r = 0.79和0.76，分别P < 0.0001）和造影剂（CM）用量相关（r = 0.77和r = 0.74，分别P < 0.0001）。在心导管穿刺后24小时，通过非对比CT评估，持续的局灶性和全局肾图通常会发生，我们的观察表明，它们可能与手术因素有关。本文的在线版本（doi:10.1007/s13244-011-0131-2）包含补充材料，仅供授权用户使用。
To describe persistent nephrographic patterns detected by unenhanced renal CT at 24 h after cardiac catheterisation and intervention. This prospective study was Health Insurance Portability and Accountability Act-compliant and institutional review board approved. Twenty-nine patients (20 men, nine women; average age 63.27 and range 41–85 years) agreed to undergo unenhanced dual-energy computed tomography (CT) limited to their kidneys at 24 h after cardiac catheterisation. CT attenuation values (Hounsfield units) were made from the cortical and medullary regions and single kidney total parenchymal iodine values (milligrams) were measured. Spearman’s rank correlation coefficient and a two-sided Fisher’s exact test were used in the statistics. Focal nephrograms were observed in at least one kidney (range, one to five regions per kidney) in 10/29 (34%) of patients and bilateral global nephrograms in 13/29 (45%) of patients. Focal nephrograms correlated with cardiac catheterisation fluoroscopic time (r = 0.48; P = 0.0087). For global nephrograms, the total iodine content of right and left kidneys correlated with fluoroscopic time (r = 0.79 and 0.76; P < 0.0001, respectively) and the amount of contrast material (CM) used (r = 0.77 and r = 0.74; P < 0.0001, respectively). Persistent focal and global nephrograms occur commonly as assessed by non-contrast CT at 24 h post cardiac catheterisation and our observations suggest they could be related to procedural factors. The online version of this article (doi:10.1007/s13244-011-0131-2) contains supplementary material, which is available to authorized users.