Associations between Pain-Related Anxiety, Gender, and Prescription Opioid Misuse among Tobacco Smokers Living with HIV/AIDS.
Associations between Pain-Related Anxiety, Gender, and Prescription Opioid Misuse among Tobacco Smokers Living with HIV/AIDS.
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艾滋病毒/艾滋病吸烟者中与疼痛相关的焦虑、性别和处方阿片类药物滥用之间的关联。
DOI：
10.1080/10826084.2018.1464028
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发表时间：
2018-11-10
影响因子：
2
通讯作者：
Ditre JW
中科院分区：
文献类型：
--
作者：
LaRowe LR;Chilcott LN;Zvolensky MJ;Vanable PA;Flood K;Ditre JW
吸烟的艾滋病毒/艾滋病感染者（PLWHA）容易受到更大的疼痛和处方止痛药的异常使用。处方阿片类药物滥用在PLWHA中非常普遍，可能导致各种不良后果。与疼痛相关的焦虑，这与维持疼痛和烟草依赖有关，也可能在处方止痛药滥用中发挥作用。本研究旨在测试疼痛相关焦虑与处方阿片类药物滥用之间的关联。我们假设，在那些处方阿片类药物中，疼痛相关焦虑与当前阿片类药物滥用呈正相关，并表明未来滥用处方阿片类药物的意图。我们进一步假设，这些关系在男性（与女性相比）中更为明显。参与者包括61名患有疼痛的PLWHA每日吸烟者。分层回归用于测试性别和疼痛相关焦虑对处方阿片类药物中当前和预期阿片类药物滥用之间的相互作用。疼痛相关焦虑和性别对阿片类药物滥用有显著的交互作用，例如，在服用阿片类药物的男性（而非女性）参与者中，疼痛相关焦虑与当前阿片类药物滥用呈正相关。在男性和女性中，疼痛相关的焦虑与将来滥用处方止痛药的意图呈正相关。需要对处方阿片类药物滥用中疼痛相关焦虑的作用进行进一步研究。这种类型的工作可能会为那些服用阿片类止痛药的PLWHA吸烟者制定量身定制的干预措施提供信息。
People living with HIV/AIDS (PLWHA) who smoke cigarettes are vulnerable to greater pain and aberrant use of prescription pain medications. Prescription opioid misuse is highly prevalent among PLWHA and can lead to a variety of adverse outcomes. Pain-related anxiety, which has been implicated in the maintenance of both pain and tobacco dependence, may also play a role in prescription pain medication misuse. This study aimed to test associations between pain-related anxiety and prescription opioid misuse. We hypothesized that, among those prescribed opioid medication, pain-related anxiety would be positively associated with current opioid misuse, and stated intentions to misuse prescription opioids in the future. We further hypothesized that these relations would be more pronounced among males (vs. females). Participants included 61 PLWHA daily tobacco smokers with pain. Hierarchical regressions were used to test interactions between gender and pain-related anxiety on current and intended opioid misuse among those prescribed opioid medications. There was a significant interactive effect of pain-related anxiety and gender on opioid misuse, such that pain-related anxiety was positively associated with current opioid misuse among male (but not female) participants who were prescribed opioid medications. Among both males and females, pain-related anxiety was positively associated with intention to misuse prescription pain medications in the future. Additional research into the role of pain-related anxiety in prescription opioid misuse is warranted. This type of work may inform the development of tailored interventions for PLWHA smokers who are prescribed opioid pain medications.
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影响因子：
4.4
作者：
Ditre, Joseph W.;Langdon, Kirsten J.;Kosiba, Jesse D.;Zale, Emily L.;Zvolensky, Michael J.
通讯作者：
Zvolensky, Michael J.
影响因子：
2.9
作者：
Dobscha, Steven K.;Morasco, Benjamin J.;Deyo, Richard A.
通讯作者：
Deyo, Richard A.
影响因子：
7.4
作者：
Butler, Stephen F.;Budman, Simon H.;Jamison, Robert N.
通讯作者：
Jamison, Robert N.
影响因子：
3.8
作者：
Bangsberg, DR;Perry, S;Moss, A
通讯作者：
Moss, A
影响因子：
4
作者：
Abrams, Murray P.;Carleton, R. Nicholas;Asmundson, Gordon J. G.
通讯作者：
Asmundson, Gordon J. G.