Sepsis-Induced Tissue Hypoperfusion
Sepsis-Induced Tissue Hypoperfusion
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DOI：
10.1016/j.ccc.2009.06.003
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发表时间：
2009-10-01
影响因子：
4.3
通讯作者：
Puskarich, Michael A.
中科院分区：
文献类型：
--
作者：
Jones, Alan E.;Puskarich, Michael A.
脓毒症通过多种机制影响心血管系统，这些紊乱通常导致组织灌注不足。组织灌注不足常出现在明显休克的情况下，但也可出现在无明显休克生理的患者中。如果不及时治疗，组织灌注不足会导致多器官功能障碍的发展，最终导致死亡。因此，临床医生了解脓毒症引起的低灌注的病理生理、识别和治疗是至关重要的。
Sepsis affects the cardiovascular system through multiple mechanisms, and often these derangements result in tissue hypoperfusion. Tissue hypoperfusion is often present in the setting of overt shock, but it can also be present in patients without obvious shock physiology. If left untreated, tissue hypoperfusion contributes to the development of multiple organ dysfunction and, ultimately, death. Therefore, it is critical for the clinician to understand the pathophysiology, recognition, and treatment of sepsis-induced hypoperfusion.