A simple method for quantitative measurement and analysis of hyperpolarized (129)Xe uptake dynamics in mouse brain under controlled flow.
A simple method for quantitative measurement and analysis of hyperpolarized (129)Xe uptake dynamics in mouse brain under controlled flow.
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一种在受控流量下定量测量和分析小鼠大脑中超极化 (129)Xe 吸收动力学的简单方法。
DOI:
10.2463/mrms.7.179
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发表时间:
2008
期刊:
影响因子:
--
通讯作者:
H. Fujiwara
中科院分区:
文献类型:
--
作者:
A. Kimura;H. Imai;T. Wakayama;H. Fujiwara
We established a simple method for measuring and quantifying uptake dynamics of hyperpolarized (HP) (129)Xe in mouse brain, which includes application of a saturation recovery pulse sequence under controlled flow of HP (129)Xe. The technique allows pursuit of the time-dependent change in (129)Xe nuclear magnetic resonance signal in the uptake process without effect from radiofrequency destruction of the polarization and the dynamics in mouse lung. The uptake behavior is well described by a simple model that depends only on a decay rate constant comprising cerebral blood flow and the longitudinal relaxation rate of HP (129)Xe in the brain tissue. The improved analysis enabled precise determination of the decay rate constant as 0.107+/-0.013 s(-1) (+/-standard deviation, n=5), leading to estimation of longitudinal relaxation time, T(1i), as 15.3+/-3.5 s.
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DOI:
--
发表时间:
2004
期刊:
International Congress Series 1265
影响因子:
--
作者:
T.Wakayama;T.Oose;M.Narazaki;A.Kimura;H.Fujiwara
通讯作者:
H.Fujiwara
DOI:
--
发表时间:
2003
期刊:
J.magn.Reson. 160
影响因子:
--
作者:
J.Fukutani;E.Suzuki;T.Shimizu;A.Kimura;H.Fujiwara
通讯作者:
H.Fujiwara
DOI:
--
发表时间:
2005
期刊:
Proceedings of 13^<th> ISMRM 13
影响因子:
--
作者:
Kimitaka Kogure;Masatoshi Ishizaki;Masaaki Nemoto;Hiroyuki Kuwano;Hiroo Hoshino;Itaru Kojima;Masatoshi Makuuchi.;Jeff Kershaw;Jeff Kershaw;中村 和浩;中村 和浩;Jeff Kershaw;Kazuhiro Nakamura;Kazuhiro Nakamura;中村 和浩;Atsushi Wakai;Jeff Kershaw
通讯作者:
Jeff Kershaw
DOI:
--
发表时间:
2004
期刊:
International Congress Series 1265
影响因子:
--
作者:
A.Kimura;T.Wakayama;M.Narazaki;Y.Kawata;T.Ueyama;H.Fujiwara
通讯作者:
H.Fujiwara
DOI:
--
发表时间:
2005
期刊:
Magnetic Resonance in Medical Sciences 4
影响因子:
--
作者:
Kimitaka Kogure;Masatoshi Ishizaki;Masaaki Nemoto;Hiroyuki Kuwano;Hiroo Hoshino;Itaru Kojima;Masatoshi Makuuchi.;Jeff Kershaw;Jeff Kershaw;中村 和浩;中村 和浩;Jeff Kershaw;Kazuhiro Nakamura;Kazuhiro Nakamura;中村 和浩;Atsushi Wakai
通讯作者:
Atsushi Wakai