Experience with antiretroviral electronic adherence monitoring among young African American men who have sex with men living with HIV: findings to inform a triaged real-time alert intervention.

Experience with antiretroviral electronic adherence monitoring among young African American men who have sex with men living with HIV: findings to inform a triaged real-time alert intervention.
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DOI:
10.1080/09540121.2020.1713975
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发表时间:
2020-09
期刊:
影响因子:
1.7
通讯作者:
Haberer JE
Haberer JE
中科院分区:
医学4区
文献类型:
--
作者:
Dworkin MS;Panchal P;Wiebel W;Garofalo R;Jimenez A;Haberer JE

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我们在芝加哥对与男性发生性行为的年轻非裔美国男性(AAMSM)进行了一项试点研究,以探索EAM的可接受性和可行性,并为干预发展提供信息。我们招募了40名接受抗逆转录病毒治疗的年轻AAMSM患者,让他们参与使用Wisepill设备进行长达3个月的监测。参与者在基线时、对第一次真正判定的1剂、3天和7天未服用的情况下以及监测结束时进行访谈。采用混合方法评估了遗漏剂量的原因以及电子监测的可接受性和可行性。参与者观察时间的中位数为90天(N=40)。在21名有90天随访的参与者中,在至少一个监测月(n=63个监测月)中,90%和80%的依从率分别为82%和79%。与会者普遍认为拟议的干预措施是可以接受和有用的。尽管有七名参与者表示,该设备吸引了人们的注意,但没有人表示这会导致他们的艾滋病毒状况被披露。这项研究发现,在芝加哥感染艾滋病毒的YAAMSM中,实时EAM是普遍可以接受和可行的。未来的工作将开发一种分类的实时eAM干预,包括检测到不遵守后的文本警报。
We performed a pilot study among young African-American men who have sex with men (AAMSM) of a real-time electronic adherence monitoring (EAM) in Chicago to explore acceptability and feasibility of EAM and to inform intervention development. We recruited 40 young AAMSM living with HIV on ART to participate in up to 3 months of monitoring with the Wisepill device. Participants were interviewed at baseline, in response to the first true adjudicated 1-dose, 3-day, and 7-day misses, and at the end of monitoring. Reasons for missing doses and the acceptability and feasibility of electronic monitoring were assessed using mixed methods. The median participant observation time was 90 days (N=40). For 21 participants with 90 days of follow-up, <90% and <80% adherence occurred in 82% and 79%, respectively in at least one of their monitored months (n=63 monitored months). The participants generally found the proposed intervention acceptable and useful. Although seven participants said the device attracted attention, none said it led to disclosure of their HIV status. This study found real-time EAM to be generally acceptable and feasible among YAAMSM living with HIV in Chicago. Future work will develop a triaged real-time EAM intervention including text alerts following detection of nonadherence.
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