Test for androgen activity at the male reproductive tract in infertile men.
Test for androgen activity at the male reproductive tract in infertile men.
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测试不育男性男性生殖道的雄激素活性。
DOI：
10.3109/01485019408987791
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
G. Gonzales
中科院分区：
文献类型：
--
作者：
G. Gonzales
进行了一项研究，以确定在基础和克罗米酚刺激后的男性血清睾酮水平和校正的精液果糖水平之间的关系。一项前瞻性对照研究在19名入选的男性中进行，这些男性参加了Instituto de Investigaciones de la Altura的男科实验室。这些受试者没有任何生殖道炎症的证据。这些男性每天接受100 mg克罗米芬，持续5天。在克罗米芬刺激之前和结束时测量血清睾酮、精液果糖和校正的果糖水平。在基础和刺激条件下，血清T水平与校正的精浆果糖比与精浆果糖浓度相关。71%的血清T水平低的受试者有低水平的校正精果糖，而只有28%的相同受试者有低水平的精果糖（未校正果糖）。结果表明，校正精浆果糖可作为生殖道雄激素活性的生物标志物。
A study was conducted to determine the relationship between levels of serum testosterone and corrected seminal fructose levels in men under basal and post-clomiphene stimulation. A prospective controlled study was carried out in 19 selected men attending the andrology laboratory at the Instituto de Investigaciones de la Altura. These subjects were without any evidence of inflammation in the reproduction tract. The men received 100 mg clomiphene citrate daily for 5 days. Serum testosterone, seminal fructose, and corrected fructose levels were measured before and at the end of clomiphene citrate stimulation. Levels of serum T were related more with corrected seminal fructose than with seminal fructose concentrations under basal and stimulated conditions. Seventy-one percent of subjects with low levels of serum T had low levels of corrected seminal fructose, whereas only 28% of the same subjects had low levels of seminal fructose (uncorrected fructose). The results suggest that corrected seminal fructose may be used as a biological marker of androgen activity in the reproductive tract.