The impact of the national stay-at-home order on emergency department visits for suspected opioid overdose during the first wave of the COVID-19 pandemic.

The impact of the national stay-at-home order on emergency department visits for suspected opioid overdose during the first wave of the COVID-19 pandemic.
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DOI:
10.1016/j.drugalcdep.2021.108977
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发表时间:
2021-11-01
影响因子:
4.2
通讯作者:
Walsh SL
Walsh SL
中科院分区:
医学2区
文献类型:
--
作者:
Root ED;Slavova S;LaRochelle M;Feaster DJ;Villani J;Defiore-Hyrmer J;El-Bassel N;Ergas R;Gelberg K;Jackson R;Manchester K;Parikh M;Rock P;Walsh SL

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尽管国家症状监测数据显示,在宣布针对 COVID-19 的全国居家令后,急诊科 (ED) 就诊人数有所下降,但很少有人知道这些下降是否是由于疑似阿片类药物过量所致。这项中断时间序列研究使用了参与治愈社区研究的四个州的症状监测数据:肯塔基州、马萨诸塞州、纽约州和俄亥俄州。 2020 年前 31 周内发生的所有疑似阿片类药物过量的急诊室 (n = 48,301) 均被纳入其中。我们研究了国家 COVID-19 公共卫生紧急事件(于 2020 年 3 月 14 日宣布)对急诊科疑似阿片类药物过量用药趋势的影响。在宣布全国公共卫生紧急状态后,四个州中的三个(马萨诸塞州、纽约州和俄亥俄州)因疑似阿片类药物过量而就诊的急诊室发生率(每 10 万人)出现统计意义上的显着下降(MA:-0.99;95 % CI:-1.75,-0.24;纽约州:-0.10;95 % CI,-0.20,0.0;OH: -0.33,95% CI:-0.58,-0.07)。此后,俄亥俄州和肯塔基州的增长率在 13 周内持续增长。纽约的 ED 发病率在 10 周内有所下降,此后发病率开始上升。在马萨诸塞州,急诊就诊率立即显着下降后,6 周内的变化率没有显着差异,随后急诊就诊率立即上升至高于新冠疫情前的水平。四个地点之间急诊科就诊趋势的异质性表明,全国居家令对每个州的阿片类药物过量急诊科表现有不同的影响。
Although national syndromic surveillance data reported declines in emergency department (ED) visits after the declaration of the national stay-at-home order for COVID-19, little is known whether these declines were observed for suspected opioid overdose. This interrupted time series study used syndromic surveillance data from four states participating in the HEALing Communities Study: Kentucky, Massachusetts, New York, and Ohio. All ED encounters for suspected opioid overdose (n = 48,301) occurring during the first 31 weeks of 2020 were included. We examined the impact of the national public health emergency for COVID-19 (declared on March 14, 2020) on trends in ED encounters for suspected opioid overdose. Three of four states (Massachusetts, New York and Ohio) experienced a statistically significant immediate decline in the rate of ED encounters for suspected opioid overdose (per 100,000) after the nationwide public health emergency declaration (MA: -0.99; 95 % CI: -1.75, -0.24; NY: -0.10; 95 % CI, -0.20, 0.0; OH: -0.33, 95 % CI: -0.58, -0.07). After this date, Ohio and Kentucky experienced a sustained rate of increase for a 13-week period. New York experienced a decrease in the rate of ED encounters for a 10-week period, after which the rate began to increase. In Massachusetts after a significant immediate decline in the rate of ED encounters, there was no significant difference in the rate of change for a 6-week period, followed by an immediate increase in the ED rate to higher than pre-COVID levels. The heterogeneity in the trends in ED encounters between the four sites show that the national stay-at-home order had a differential impact on opioid overdose ED presentation in each state.
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