Mass Spectrometric Analysis of Mitochondrial RNA Modifications
Mass Spectrometric Analysis of Mitochondrial RNA Modifications
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线粒体 RNA 修饰的质谱分析
DOI:
10.1007/978-1-0716-0834-0_8
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发表时间:
2020
影响因子:
--
通讯作者:
Suzuki Takeo
中科院分区:
文献类型:
--
作者:
Ishigami Yuma;Suzuki Tsutomu;Suzuki Takeo
Mitochondrial RNAs are modified posttranscriptionally. These modifications are required for proper functioning of RNA molecules, and thereby contribute to essential mitochondrial processes. Herein, we describe our latest mass spectrometry-based platform for analysis of posttranscriptional modifications of mitochondrial tRNAs, and measuring the in vitro activity of mitochondrial RNA-modifying enzymes.