CYSTIC FLUID IN CRANIOPHARYNGIOMAS - MR IMAGING AND QUANTITATIVE-ANALYSIS
CYSTIC FLUID IN CRANIOPHARYNGIOMAS - MR IMAGING AND QUANTITATIVE-ANALYSIS
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DOI：
10.1148/radiology.182.3.1535894
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发表时间：
1992-03-01
期刊：
影响因子：
19.7
通讯作者：
ZEE, CS
中科院分区：
文献类型：
--
作者：
AHMADI, J;DESTIAN, S;ZEE, CS
我们对10例颅咽管瘤中的囊液进行了一项前瞻性研究，以将T1加权磁共振（MR）图像上的信号强度与生化分析相关联。 术前2天内，每例患者在钆喷酸葡胺给药前后接受MR成像。 5例患者的囊液信号强度低于白色物质，蛋白质水平低于9，000 mg/dL（90.00 g/L），无游离高铁血红蛋白。 在所有10例患者中，1/5例患者的甘油三酯浓度最高（84 mg/dL [0.95 mmol/L]）;另1/5例患者的胆固醇浓度最高（270 mg/dL [6.98 mmol/L]）。 结论：颅咽管瘤囊液在T1加权MR图像上的信号强度增加可能是由蛋白质浓度大于或等于9,000 mg/dL（90.00 g/L）、游离高铁血红蛋白的存在或两者兼而有之引起的。 在本研究测量的浓度范围内，胆固醇和甘油三酯未增加信号强度。
A prospective study of cystic fluid in craniopharyngiomas in 10 patients was performed to correlate signal intensity on T1-weighted magnetic resonance (MR) images and biochemical analysis. Within 2 days before surgery, each patient underwent MR imaging before and after administration of gadopentetate dimeglumine. Five patients had cystic fluid lower in signal intensity than white matter, with protein levels less than 9,000 mg/dL (90.00 g/L) and no free methemoglobin. One of the five patients had the highest triglyceride concentration (84 mg/dL [0.95 mmol/L]) of all 10 patients; another of these five had the highest cholesterol concentration of all (270 mg/dL [6.98 mmol/L]). It is concluded that the increased signal intensity of cystic fluid in craniopharyngiomas on T1-weighted MR images can be caused by a protein concentration greater than or equal to 9,000 mg/dL (90.00 g/L), the presence of free methemoglobin, or both. In the ranges of concentrations measured in this study, cholesterol and triglyceride did not increase signal intensity.