Locoregional extension patterns of nasopharyngeal carcinoma and suggestions for clinical target volume delineation
Locoregional extension patterns of nasopharyngeal carcinoma and suggestions for clinical target volume delineation
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DOI：
10.5732/cjc.012.10095
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发表时间：
2012-12-01
影响因子：
--
通讯作者：
Ma, Jun
中科院分区：
文献类型：
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作者：
Li, Wen-Fei;Sun, Ying;Ma, Jun
临床靶区(CTV)的确定对肿瘤控制和正常组织保护至关重要。本研究旨在明确鼻咽癌(NPC)的局部区域扩散模式，并提高CTV显示效果。对2366例新诊断的鼻咽癌患者进行了磁共振成像检查。根据肿瘤侵袭的发生率，鼻咽周围的解剖部位被分为高危(30%)、中危(5%-30%)和低危(5%-30%)。
Clinical target volume (CTV) delineation is crucial for tumor control and normal tissue protection. This study aimed to define the locoregional extension patterns of nasopharyngeal carcinoma (NPC) and to improve CTV delineation. Magnetic resonance imaging scans of 2366 newly diagnosed NPC patients were reviewed. According to incidence rates of tumor invasion, the anatomic sites surrounding the nasopharynx were classified into high-risk (>30%), medium-risk (5%-30%), and low-risk (