Medium‐chain triglycerides modulate ileitis induced by trinitrobenzene sulfonic acid

Medium‐chain triglycerides modulate ileitis induced by trinitrobenzene sulfonic acid
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中链甘油三酯调节三硝基苯磺酸引起的回肠炎

DOI:
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发表时间:
1999
影响因子:
4.1
通讯作者:
T. Bamba
T. Bamba
中科院分区:
医学3区
文献类型:
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作者:
T. Tsujikawa;N. Ohta;Tsuyoshi Nakamura;J. Satoh;K. Uda;T. Ihara;Toshihiko Okamoto;Y. Araki;A. Andoh;M. Sasaki;Y. Fujiyama;T. Bamba

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背景:开发合适的动物模型对于进一步研究炎症性肠病(IBD)非常重要。因此,我们研究了三硝基苯磺酸(TNBS)回肠炎模型。克罗恩病中的膳食脂肪仍然是 IBD 的一个有争议的危险因素。因此,我们还研究了中链甘油三酯 (MCT) 和长链甘油三酯 (LCT) 对 TNBS 回肠炎的影响。
Background : It is important to develop an appropriate animal model for further investigation into inflammatory bowel disease (IBD). We therefore investigated a trinitrobenzene sulfonic acid (TNBS) ileitis model. Dietary fat in Crohn’s disease is still a controversial risk factor for IBD. We therefore also studied the effects of medium‐chain triglycerides (MCT) and long‐chain triglycerides (LCT) on TNBS ileitis.