Comparison of influenza A and influenza B virus infection in hospitalized children
Comparison of influenza A and influenza B virus infection in hospitalized children
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DOI：
10.1046/j.1440-1754.2000.00533.x
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发表时间：
2000-08-01
影响因子：
1.7
通讯作者：
Isaacs, D
中科院分区：
文献类型：
--
作者：
Daley, AJ;Nallusamy, R;Isaacs, D
背景：1997年冬天，甲型和乙型流感病毒在澳大利亚流行。目的：比较某儿科三级转诊中心收治的甲型或乙型流感患儿的临床和人口学特征。方法：回顾1997年经培养证实为甲型或乙型流感的91例住院患儿的临床和人口学特征。结果：甲型流感患儿中36例(56%)年龄在12个月以下，而27例乙型流感患儿中有7例(26%)12个月以下。B型流感病毒感染在有潜在健康问题的儿童中更为常见(P=0.01)。甲型流感患儿8例(12.5%)有神经系统症状，无乙型流感病毒感染者(P=0.09)。甲型和乙型流感患儿在体征症状、病情严重程度、住院天数等方面差异无统计学意义。结论：甲型流感患儿中12个月以下比例较大。B型流感病毒感染更多地与潜在的医疗疾病有关。甲型或乙型流感病毒感染与临床症状和体征不能区分。
Background: Influenza A and B viruses were cocirculating in Australia in the winter of 1997. Objective: To compare the clinical and demographic features of children with influenza A or influenza B virus infection admitted to a paediatric tertiary referral centre.Methodology: Retrospective chart review of 91 hospitalized children with culture-proven influenza A or B virus infection during 1997.Results: Thirty-six (56%) of 64 children with influenza A were under 12 months of age compared with seven (26%) of 27 children with influenza B virus infection (P = 0.02). Influenza B virus infection was more common in children with underlying medical problems (P = 0.01). Neurological manifestations were present in eight (12.5%) of 64 children with influenza A and none with influenza B virus infection (P = 0.09). There were no significant differences in signs and symptoms of children with influenza A and B virus infection, in severity of illness or in duration of hospital stay.Conclusions: A greater proportion of children admitted with influenza A virus infection were under 12 months of age. Influenza B virus infection is associated more commonly with underlying medical disorders. It is not possible to differentiate between influenza A or B virus infection from presenting clinical signs and symptoms.