Sleep restriction can attenuate prioritization benefits on declarative memory consolidation.
Sleep restriction can attenuate prioritization benefits on declarative memory consolidation.
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DOI：
10.1111/jsr.12424
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发表时间：
2016-12
影响因子：
4.4
通讯作者：
Chee MW
中科院分区：
文献类型：
--
作者：
Lo JC;Bennion KA;Chee MW
由于慢性睡眠限制是青少年中普遍存在的问题，本研究调查了1周睡眠限制（SR）与对照期对散文段落长期记忆巩固的影响。我们还确定了记忆优先化的好处是否受到巩固期间充足睡眠的调节。56名健康青少年（25名男性，年龄15-19岁）被要求记住一篇散文，其中一半的内容被突出显示（优先级），并被告知他们将获得额外的奖励。在最初的自由回忆测试之后，参与者经历了7个晚上的时间，在此期间，他们接受了5小时（SR）或9小时（对照）的夜间睡眠机会，并在选定的夜晚通过多导睡眠图进行监测。在睡眠操作期结束时（编码后1周）测试文章的自由回忆，并在编码后6周再次测试。在所有三个时间点（初始、1周、6周），突出显示内容的回忆率均优于非突出显示内容的回忆率（上级）。相对于对照组编码后的几分钟，优先级对记忆的这种有益影响在1周内更强，但SR组则不然。对照组和SR组的N3持续时间相似。总的来说，目前的研究表明，记忆优先级的好处随着时间的推移而增强，需要时间和睡眠才能充分发挥作用。部分睡眠剥夺（即5小时夜间睡眠机会）可能会削弱这些益处，但这可能会被N3睡眠持续时间的保留所抵消。
As chronic sleep restriction is a widespread problem among adolescents, the present study investigated the effects of a 1‐week sleep restriction (SR) versus control period on the consolidation of long‐term memory for prose passages. We also determined whether the benefit of prioritization on memory is modulated by adequate sleep occurring during consolidation. Fifty‐six healthy adolescents (25 male, aged 15–19 years) were instructed to remember a prose passage in which half of the content was highlighted (prioritized), and were told that they would receive an additional bonus for remembering highlighted content. Following an initial free recall test, participants underwent a 7‐night period in which they received either a 5‐h (SR) or 9‐h (control) nightly sleep opportunity, monitored by polysomnography on selected nights. Free recall of the passage was tested at the end of the sleep manipulation period (1 week after encoding), and again 6 weeks after encoding. Recall of highlighted content was superior to that of non‐highlighted content at all three time‐points (initial, 1 week, 6 weeks). This beneficial effect of prioritization on memory was stronger 1 week relative to a few minutes after encoding for the control, but not the SR group. N3 duration was similar in the control and SR groups. Overall, the present study shows that the benefits of prioritization on memory are enhanced over time, requiring time and sleep to unfold fully. Partial sleep deprivation (i.e. 5‐h nocturnal sleep opportunity) may attenuate such benefits, but this may be offset by preservation of N3 sleep duration.