[Chemotherapy of the non-small cell bronchogenic carcinoma].

[Chemotherapy of the non-small cell bronchogenic carcinoma].
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非小细胞支气管癌的化疗[J].

DOI:
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发表时间:
1983
期刊:
影响因子:
0.3
通讯作者:
S. Safarini
S. Safarini
中科院分区:
--
文献类型:
--
作者:
K. Dimitriadis;L. Boutis;J. Tavantzis;D. Mouratidou;N. Bouchoris;S. Koukourikos;K. Hatzigogos;S. Safarini

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From 1976 to 1981 61 patients (50 men and 11 women) with non-small cell bronchogenic carcinoma (i.e. squamous cell or adeno-carcinoma) received a chemotherapy treatment based on two cytostatic drug combinations for each histological group. The drugs which were used were cyclophosphamide, adriamycin, vincristine, methotrexate, bleomycin, 5-fluorouracil and procarbazine. All patients had advanced disease and 6 of them had had previous surgical excision of the primary tumor. A large proportion of the patients had received irradiation to the primary site prior to chemotherapy. 1 patient developed a complete remission, 5 developed a partial remission and 34 showed stabilization of their disease. In 21 patients the disease progressed in spite of the treatment. Responders had a significantly longer survival than non-responding patients.