Abscisic acid and abiotic stress tolerance - Different tiers of regulation
Abscisic acid and abiotic stress tolerance - Different tiers of regulation
复制标题
DOI：
10.1016/j.jplph.2013.12.007
复制
发表时间：
2014-04-15
影响因子：
4.3
通讯作者：
Mehrotra, Sandhya
中科院分区：
文献类型：
--
作者：
Mehrotra, Rajesh;Bhalothia, Purva;Mehrotra, Sandhya
非生物胁迫严重影响植物的生长、代谢和可持续性，阻碍植物的生产力。植物以无数种方式对抗这些压力。通过对非生物胁迫耐受性机制的分析，我们发现了一条由磷酸酶、激酶、转录因子和其他调控元件组成的高度复杂而又受到严格调控的信号转导通路。越来越清楚的是，在对抗应激条件下，表观遗传过程也与aba介导的基因表达协同合作。动态应激诱导机制，包括ABA的外胞体库的变化，通过一系列磷酸酶和激酶传递，导致应激诱导基因的表达。涉及DNA甲基化和染色质修饰的过程以及转录后、翻译后和表观遗传控制机制，形成多层调控，调控该基因的表达。随着转基因技术的最新进展，现在已经有可能在诱导启动子的控制下设计表达胁迫诱导基因的植物，提高它们抵御不利条件的能力。本文就ABA的合成、ABA信号转导途径的组成以及植物在遗传和表观遗传水平上的反应作一综述。它进一步关注rna在调控胁迫反应中的作用以及开发耐胁迫转基因植物的各种方法。(C) 2013爱思唯尔有限公司版权所有。
Abiotic stresses affect plant growth, metabolism and sustainability in a significant way and hinder plant productivity. Plants combat these stresses in myriad ways. The analysis of the mechanisms underlying abiotic stress tolerance has led to the identification of a highly complex, yet tightly regulated signal transduction pathway consisting of phosphatases, kinases, transcription factors and other regulatory elements. It is becoming increasingly clear that also epigenetic processes cooperate in a concerted manner with ABA-mediated gene expression in combating stress conditions. Dynamic stress-induced mechanisms, involving changes in the apoplastic pool of ABA, are transmitted by a chain of phosphatases and kinases, resulting in the expression of stress inducible genes. Processes involving DNA methylation and chromatin modification as well as post transcriptional, post translational and epigenetic control mechanisms, forming multiple tiers of regulation, regulate this gene expression. With recent advances in transgenic technology, it has now become possible to engineer plants expressing stress-inducible genes under the control of an inducible promoter, enhancing their ability to withstand adverse conditions. This review briefly discusses the synthesis of ABA, components of the ABA signal transduction pathway and the plants' responses at the genetic and epigenetic levels. It further focuses on the role of RNAs in regulating stress responses and various approaches to develop stress-tolerant transgenic plants. (C) 2013 Elsevier GmbH. All rights reserved.