CLASSIFICATION OF CHRONIC HEPATITIS - DIAGNOSIS, GRADING AND STAGING

CLASSIFICATION OF CHRONIC HEPATITIS - DIAGNOSIS, GRADING AND STAGING
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DOI:
10.1016/0270-9139(94)90250-x
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发表时间:
1994-06-01
期刊:
影响因子:
13.5
通讯作者:
SCHEUER, PJ
SCHEUER, PJ
中科院分区:
医学1区
文献类型:
--
作者:
DESMET, VJ;GERBER, M;SCHEUER, PJ

文献摘要

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慢性肝炎的第一个分类是在25年前提出的(1)。当时慢性肝炎的病因尚不清楚,大多数病例被认为是自身免疫性肝炎(所谓的狼疮样肝炎)(2)。提出的分类旨在根据疾病活动程度区分亚组,为使用免疫抑制治疗提供预后信息和标准。在最初的分类中,区分了较温和的疾病类别,称为慢性持续性肝炎,和具有更严重疾病活动的变体,称为慢性侵袭性肝炎。
A first classification of chronic hepatitis was proposed25 years ago (1). At that time the causes of chronic hepatitis were largely unknown, and most cases were assumed to be autoimmune in nature (so-called lupoid hepatitis)(2). The proposed classification was aimed at distinguishing subgroups according to the degree of disease activity to provide prognostic information and criteria for the use of immunosuppressive therapy. In the initial classification, distinction was made between a milder category of disease, termed chronic persistent hepatitis, and variants with more severe disease activity, termed chronic aggressive hepatitis.