Organization of the hamster paraventricular hypothalamic nucleus.
Organization of the hamster paraventricular hypothalamic nucleus.
复制标题
仓鼠下丘脑室旁核的组织。
DOI：
10.1002/cne.903320307
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Blanchard,J
中科院分区：
文献类型：
--
作者：
Morin,LP;Blanchard,J
仓鼠下丘脑脑室周围区域一直是光周期时间测量功能研究的焦点。这些研究依赖于对大鼠室旁核的广泛分析，因为普遍缺乏仓鼠的解剖学描述。目前的工作是通过研究仓鼠室旁核的结构来解决这个问题，即对加压素、催产素或促肾上腺皮质激素释放因子产生免疫反应的细胞的定位，以及投射到脊髓或血脑屏障外血管部位的细胞的定位。仓鼠室旁核包括内侧、外侧和后大细胞分裂、主要的小细胞分裂以及脑室周围区域和背帽，也是小细胞的。大细胞分裂的特征是许多对催产素和加压素有免疫反应的大神经元，而小细胞分裂通常不存在这些神经元。相比之下，大多数小细胞区域都有大量促肾上腺皮质激素释放激素免疫反应细胞。脊柱突出细胞存在于两个吻侧区域，一个位于背侧，第二个位于腹侧区域。在尾部，这两个区域在后大细胞分裂内合并。腹侧组的细胞经常对三种肽之一产生免疫反应。通过外周注射逆行标记鉴定的细胞存在于吻侧大细胞分裂中，但未存在于尾侧后大细胞分裂中。还描述了这些细胞也含有肽的区域。将仓鼠室旁核的特征与大鼠的室旁核特征进行比较，并讨论明显的物种差异。 © 1993 Wiley-Liss, Inc.
The hamster periventricular hypothalamic area has been the focus of functional research concerning photoperiodic time measurement. These studies have relied upon the extensive analysis of rat paraventricular nucleus because there has been a general absence of anatomical description in the hamster. The present work southt to remedy this problem by investigating the structure of the hamster paraventricular nucleus with respect to the localization of cells immunoreactive to vasopressin, oxytocin, or cotricotropin‐releasing factor and of cells projecting to the spinal cord or to vascular sites outside the blood‐brain barrier.The hamster paraventricular nucludus includes the medial, lateral, and posterior magnocellular divisions, the main parvicellular division, as well as the periventricular area and dorsal cap, which are also parvicellular. The magnocellular divisions are characterized by many large neurons immunoreactive to oxytocin and vasopressin, which are generally absent from the parvicellular divisions. In contrast, corticotrophin‐releasing hormone‐immunoreactive cells are plentiful in most of the parvicellular areas. Spinally projecting cells are found in two rostral areas, one dorsally and a second, more ventral area. More caudally, the two regions merge within the posterior magnocellular division. Cells of the ventral group are frequently immunoreactive for one of the three peptides. Cells identified by peripheral injection of retrograde label are found in the rostral magnocellular divisons but not in the caudal posterior magnocellular division. Areas in which these cells also contain peptide are also described. The features of the hamster paraventricular nucleus are compared to those in the rat and apparent species differences are discussed. © 1993 Wiley‐Liss, Inc.