Facing Challenges in Real-Life Application of Surface-Enhanced Raman Scattering: Design and Nanofabrication of Surface-Enhanced Raman Scattering Substrates for Rapid Field Test of Food Contaminants
Facing Challenges in Real-Life Application of Surface-Enhanced Raman Scattering: Design and Nanofabrication of Surface-Enhanced Raman Scattering Substrates for Rapid Field Test of Food Contaminants
复制标题
表面增强拉曼散射在实际应用中面临的挑战：用于食品污染物快速现场测试的表面增强拉曼散射基底的设计和纳米制造
DOI：
10.1021/acs.jafc.7b03075
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发表时间：
2018-07-04
影响因子：
6.1
通讯作者：
Ying, Yibin
中科院分区：
文献类型：
--
作者：
Shi, Ruyi;Liu, Xiangjiang;Ying, Yibin
表面增强拉曼散射（SERS）能够高特异性地检测单分子，已成为农产品和食品快速化学分析的一项有前景的技术。随着对 SERS 效应的深入了解和纳米制造技术的进步，SERS 现在即将走出实验室，成为完成各种现实世界任务的复杂分析工具。本文重点讨论了SERS在这一进展中遇到的挑战，例如如何获得可靠的SERS信号、提高复杂样品基质中的灵敏度和特异性、开发简单且用户友好的实用传感方法、降低运行成本等。本文重点介绍了SERS活性基底的设计和纳米加工以解决这些挑战的新思路，并介绍了SERS在该领域应用的最新进展。我们希望我们的讨论能够鼓励更多的研究来应对这些挑战，并最终帮助将 SERS 技术带出实验室。
Surface-enhanced Raman scattering (SERS) is capable of detecting a single molecule with high specificity and has become a promising technique for rapid chemical analysis of agricultural products and foods. With a deeper understanding of the SERS effect and advances in nanofabrication technology, SERS is now on the edge of going out of the laboratory and becoming a sophisticated analytical tool to fulfill various real-world tasks. This review focuses on the challenges that SERS has met in this progress, such as how to obtain a reliable SERS signal, improve the sensitivity and specificity in a complex sample matrix, develop simple and user-friendly practical sensing approach, reduce the running cost, etc. This review highlights the new thoughts on design and nanofabrication of SERS-active substrates for solving these challenges and introduces the recent advances of SERS applications in this area. We hope that our discussion will encourage more researches to address these challenges and eventually help to bring SERS technology out of the laboratory.