Tailored Text Messaging Intervention for HIV Adherence: A Proof-of-Concept Study
Tailored Text Messaging Intervention for HIV Adherence: A Proof-of-Concept Study
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DOI：
10.1037/a0028109
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发表时间：
2013-03-01
影响因子：
4.2
通讯作者：
Kuhns, Lisa M.
中科院分区：
文献类型：
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作者：
Lewis, Megan A.;Uhrig, Jennifer D.;Kuhns, Lisa M.
目的：本研究旨在确定通过短信向艾滋病毒感染者（PLWH）提供的动态定制药物信息是否会受到欢迎，并提高依从性和临床结果。研究方法：一项实验前的概念验证研究，涉及52名从健康诊所招募的男男性行为者（MSM），重点是促进男同性恋，女同性恋，双性恋和变性人的福祉。入选标准为讲英语的HIV阳性MSM，年龄在25岁或以上。参与者还必须同意允许访问他们的医疗记录、拥有手机并能够在3个月的干预期内接收短信。参与者完成了评估各种人口统计学，社会和健康问题的基线调查;在3个月内收到短信;通过双向消息回答每周的依从性问题;并在干预期结束时完成了随访调查。临床结果是从参与者的基线和随访的医疗记录中提取的。自我报告的药物依从性和临床结局，包括CD 4计数和病毒载量。结果：参与者接受短信干预，并报告阅读和喜欢的消息。自我报告的药物依从性显着改善参与者谁开始研究作为非依从性，并收到定制的药物提醒。从基线至随访，总体病毒载量显著降低，CD 4计数显著增加。结论：结果表明，使用双向短信动态定制的依从性消息，可以提高依从性和改善PLWH的重要临床结果。
Objective: This study sought to determine if dynamically tailored medication messages delivered to people living with HIV (PLWH) via text messaging would be well received and enhance adherence and clinical outcomes. Methods: A preexperimental proof-of-concept study with 52 men who have sex with men (MSM) recruited from a health clinic focused on promoting the well-being of gay, lesbian, bisexual, and transgender people. Inclusion criteria were being an English speaking HIV-positive MSM, aged 25 or older. Participants also had to agree to allow access to their medical records, have a cell phone, and be able to receive text messages over the 3-month intervention period. Participants completed baseline surveys that assessed various demographic, social, and health questions; received text messages over 3 months; answered weekly adherence questions via two-way messaging; and completed a follow-up survey at the end of the intervention period. Clinical outcomes were abstracted from participants' medical records at baseline and follow-up. Self-reported medication adherence and clinical outcomes, including CD4 counts and viral load. Results: Participants were receptive to the text messaging intervention, and reported reading and liking the messages. Self-reported medication adherence significantly improved among participants who began the study as nonadherent and received tailored medication reminders. Overall viral load significantly decreased and CD4 count significantly increased from baseline to follow-up. Conclusions: The results demonstrate that using two-way text messaging to dynamically tailor adherence messages may enhance adherence and improve important clinical outcomes for PLWH.