Obesity and Undernutrition in Acute Myocardial Infarction.
Obesity and Undernutrition in Acute Myocardial Infarction.
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急性心肌梗死中的肥胖和营养不良。
DOI：
10.1016/j.amjcard.2023.07.111
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Nanna,MichaelG
中科院分区：
文献类型：
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作者：
Mangalesh,Sridhar;Nanna,MichaelG
营养状况是本次分析中关注的主要预测变量，其与其他几个变量之间的密切相关性提出了重要的问题。众所周知，营养不良和肥胖是共存的，并且营养不良已被证明可以预测不良结果，与肥胖无关，3, 4 例如肥胖营养不良合并心力衰竭的患者。 5 鉴于肥胖和营养不良之间的潜在相互作用，值得注意的是，在按肥胖进行分组后，本研究中营养不良的表现如何，以及相互作用项是否显着。[...]明确当前分析中哪个具体标准主导了营养不良的分类，将为对该队列中营养不良表型的适当解释提供信息。竞争利益声明 Nanna 博士报告了 HeartFlow, Inc. 的咨询费用。Mangalesh 博士没有需要声明的竞争利益。资助 Nanna 博士报告了来自华盛顿哥伦比亚特区美国心脏病学院（乔治 F 和安哈里斯贝洛斯基金会）、华盛顿哥伦比亚特区以患者为中心的结果研究所以及马里兰州贝塞斯达国家老龄化研究所/国家卫生研究院的资助，GEMSSTAR 奖：
Nutritional status is the principal predictor variable of interest in this analysis, and the nature of its strong associations with several other variables raises important questions. Poor nutritional status and obesity are known to co-exist, and malnutrition has been demonstrated to predict poor outcomes independent of obesity, 3, 4 such as in obese-malnourished patients with heart failure. 5 In light of the potential interplay between obesity and undernutrition, it would be interesting to note how undernutrition performs in the present study after subgrouping by obesity and whether an interaction term emerges as significant.[...] clarity on which of the specific criteria dominated the classification of undernutrition in the present analysis would inform the appropriate interpretation of the undernutrition phenotype represented in this cohort. Declaration of Competing Interest Dr. Nanna reports consulting fees from HeartFlow, Inc. Dr. Mangalesh has no competing interests to declare. Funding Dr. Nanna reports funding from the American College of Cardiology, Washington, District of Columbia (George F and Ann Harris Bellows Foundation), the Patient-Centered Outcomes Research Institute, Washington, District of Columbia, and the National Institute on Aging/National Institutes of Health, Bethesda, Maryland, GEMSSTAR award: