Synchrotron microangiography with no contrast agent
Synchrotron microangiography with no contrast agent
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DOI：
10.1088/0031-9155/49/4/002
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发表时间：
2004-02-21
影响因子：
3.5
通讯作者：
Seong, JK
中科院分区：
文献类型：
--
作者：
Hwu, Y;Tsai, WL;Seong, JK
来自同步加速器源的相干x射线越来越多地用于非常规放射技术（“相衬”放射学）。我们的实验表明，通过使用白色（非单色）辐射和时间分辨系统，可以在不使用任何造影剂的情况下对不同活体动物中运动血管的微观细节进行成像。图像具有出色的对比度和前所未有的空间分辨率，用于微血管造影（< 10 μ m）。这一结果很可能影响到生物学和医学研究以及放射诊断学的许多不同领域。
Coherent x-rays from synchrotron sources are increasingly used in non-conventional radiological techniques ('phase-contrast' radiology). Our experiments demonstrate that by using white (unmonochromatic) radiation and a time-resolving system, it is possible to image microscopic details of moving blood vessels in different live animals without using any contrast agent. The images have excellent contrast plus unprecedented spatial resolution for microangiography (< 10 mum). This result is likely to impact many different areas of biological and medical research and of diagnostic radiology.