The Mini-Cog as a screen for dementia: Validation in a population-based sample

The Mini-Cog as a screen for dementia: Validation in a population-based sample
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DOI:
10.1046/j.1532-5415.2003.51465.x
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发表时间:
2003-10-01
影响因子:
6.3
通讯作者:
Ganguli, M
Ganguli, M
中科院分区:
医学1区
文献类型:
--
作者:
Borson, S;Scanlan, JM;Ganguli, M

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目的:在美国老年人痴呆的流行病学研究中测试Mini-Cog,一种简短的认知筛查测试。设计:在现有数据集中对Mini-Cog检测痴呆的敏感性和特异性进行基于人群的事后检查。周边环境:宾夕法尼亚州西部的莫农加希拉山谷(Monongahela Valley)。参与者:随机抽取1119名老年人参加莫农加希拉谷独立老年人调查(电影)。测量:将Mini-Cog在检测独立诊断的痴呆方面的有效性与Mini-Mental State Examination (MMSE)和标准化神经心理学电池的有效性进行比较。结果:Mini-Cog被算法评分为“可能受损”或“可能正常”,MMSE在临界值为25时,对痴呆症具有相似的敏感性(76%对79%)和特异性(89%对88%),与使用传统神经心理学电池(75%敏感性,90%特异性)相当。结论:当在现有人群中应用后,Mini-Cog在检测痴呆方面与更长的筛查和评估工具一样有效。当目标是提高对可能有认知障碍的老年人的识别时,它的简洁是一个明显的优势。先前在多种族社区样本中表现良好的证据进一步支持了其在美国种族语言多样化人群中的有效性,在这些人群中,广泛使用的认知屏幕经常失败。
OBJECTIVES: To test the Mini-Cog, a brief cognitive screening test, in an epidemiological study of dementia in older Americans.DESIGN: A population-based post hoc examination of the sensitivity and specificity of the Mini-Cog for detecting dementia in an existing data set.SETTING: The Monongahela Valley in Western Pennsylvania.PARTICIPANTS: A random sample of 1,119 older adults enrolled in the Monongahela Valley Independent Elders Survey (MoVIES).MEASUREMENTS: The effectiveness of the Mini-Cog in detecting independently diagnosed dementia was compared with that of the Mini-Mental State Examination (MMSE) and a standardized neuropsychological battery.RESULTS: The Mini-Cog, scored by an algorithm as "possibly impaired'' or "probably normal,'' and the MMSE, at a cutpoint of 25, had similar sensitivity (76% vs 79%) and specificity (89% vs 88%) for dementia, comparable with that achieved using a conventional neuropsychological battery (75% sensitivity, 90% specificity).CONCLUSION: When applied post hoc to an existing population, the Mini-Cog was as effective in detecting dementia as longer screening and assessment instruments. Its brevity is a distinct advantage when the goal is to improve identification of older adults in a population who may be cognitively impaired. Prior evidence of good performance in a multiethnic community-based sample further supports its validity in the ethnolinguistically diverse populations of the United States in which widely used cognitive screens often fail.