fMRI study of taste cortical areas in humans
fMRI study of taste cortical areas in humans
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DOI：
10.1111/j.1749-6632.1998.tb10623.x
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发表时间：
1998-01-01
期刊：
影响因子：
--
通讯作者：
Pillias, AM
中科院分区：
文献类型：
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作者：
Faurion, A;Cerf, B;Pillias, AM
我们使用3特斯拉功能磁共振成像（fMRI）与回波平面成像映射人类的味觉投射。激活区位于外侧裂周围或深埋于外侧裂内，激活区主要位于小脑上半部、额盖、中央前回和中央后回的底部。此外，我们可以描述，为第一次，位于主体（n = 10）的优势半球的下部的偏侧联想投影。我们还观察到前扣带回、丘脑中央内侧区和其他与情绪或认知过程相关的区域的激活。30名受试者接受了一项熟悉实验，对新恐惧和非新恐惧刺激进行取样。等强度浓度的测量，幅度估计和享乐价值进行了评估，重复10周。5名被试分别在熟悉前、熟悉中和熟悉后进行了3次fMRI实验，心理物理数据显示了享乐评价的演变与感知强度的关系，fMRI结果显示了享乐评价的演变与味觉皮层区激活像素百分比的演变之间的关系。
We used 3 Tesla functional magnetic resonance imaging (fMRI) with echo planar imaging to map taste projections in the human. Activations were found surrounding and buried in the sylvian fissure; the upper part of insula, the frontal operculum, and the foot of the pre- and postcentral gyri were usually activated. Moreover, we could describe, for the first time, a lateralized associative projection located in the lower part of the dominant hemisphere of the subject (n = 10). We also observed activations in the anterior cingulate gyrus, the centromedial thalamus, and other areas related to emotional or cognitive processes.Thirty subjects were submitted to a familiarization experiment sampling neophobic and nonneophobic stimuli. Measurements of isointense concentrations, magnitude estimates and hedonic values were assessed repetitively for 10 weeks. Five subjects performed 3 fMRI experiments, before, during and after familiarization.Psychophysical data showed a relationship between the evolution of the hedonic assessment and the intensity of the perception, and fMRI results showed a relationship between the evolution of the hedonic assessment and the evolution of the percent of activated pixels in taste cortical area.