PATTERNS OF INTERCELLULAR CONNECTIVITY IN THE MAMMALIAN CUMULUS-OOCYTE COMPLEX
PATTERNS OF INTERCELLULAR CONNECTIVITY IN THE MAMMALIAN CUMULUS-OOCYTE COMPLEX
复制标题
DOI：
10.1002/jemt.1070270206
复制
发表时间：
1994-02-01
影响因子：
2.5
通讯作者：
RIDER, V
中科院分区：
文献类型：
--
作者：
ALBERTINI, DF;RIDER, V
电子显微镜和荧光显微镜技术已被用于以互补的方式研究卵泡细胞卵母细胞的相互作用的模式内的卵丘卵母细胞复合物的各种哺乳动物。主要调查结果是：（1）存在两种不同类型的跨带过程，它们可以根据细胞骨架组成进行区分;（2）在所研究的一些物种中，（猪、山羊、灵长类），螺旋状突起富含微管蛋白，穿过透明质膜并内陷到卵母细胞皮层;（3）富含肌动蛋白的突起或在卵膜外表面形成网状分枝，或以种特异的方式穿透卵膜与卵膜接触。这些结果进行了讨论，相对于需要采用互补的光学方法在评估COC内的连接模式和细胞外基质-细胞相互作用的卵母细胞的生长和成熟的稳态控制中发挥的可能作用。
Electron and fluorescence microscopic techniques have been used in a complementary fashion to study the patterns of follicle cell-oocyte interactions within cumulus-oocyte-complexes of various mammals. The principal findings are: (1) two distinct types of transzonal processes exist that are distinguishable on the basis of cytoskeletal composition; (2) in some of the species examined (pig, goat, primate), corkscrew-shaped processes rich in tubulin, traverse the zona pellucida and are invaginated into the oocyte cortex; (3) actin-rich processes either ramify as a network at the outer surface of the zona pellucida or penetrate the zona and make contact with the oolemma in a species specific manner. These results are discussed with respect both to the need to employ complementary optical methods in assessing connectivity patterns within COC and to the possible role that extracellular matrix-cell interactions play in the homeostatic control of oocyte growth and maturation.