Lung development
Lung development
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DOI：
10.1053/j.sempedsurg.2015.01.011
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发表时间：
2015-08-01
影响因子：
1.7
通讯作者：
Smith, Nicola P.
中科院分区：
文献类型：
--
作者：
Mullassery, Dhanya;Smith, Nicola P.
人类肺的发育始于妊娠第4周，前肠开始出现气管，并一直持续到儿童早期。出生时的存活取决于子宫内肺的充分发育和成熟。支气管肺发育异常会导致先天性肺畸形，而发育不足被认为会导致支气管肺发育不良。影响肺部发育的复杂过程和因素正开始被阐明，进一步的知识将有望导致改善干预措施，以提高易感或受影响婴儿的预后。(C) 2015爱思唯尔公司版权所有。
The development of the human lung starts at 4 weeks of gestation with the appearance of the tracheal outgrowth from the foregut and continues into early childhood. Survival at birth is dependent on adequate development and maturation of the lung in utero. Abnormal bronchopulmonary development results in congenital lung malformations, and inadequate development is thought to contribute to bronchopulmonary dysplasia. Complex processes and factors influencing lung development are beginning to be elucidated, and further knowledge will hopefully lead to improved interventions to enhance outcomes in vulnerable or affected infants. (C) 2015 Elsevier Inc. All rights reserved.