The Great Chinese Famine Leads to Shorter and Overweight Females in Chongqing Chinese Population After 50 Years
The Great Chinese Famine Leads to Shorter and Overweight Females in Chongqing Chinese Population After 50 Years
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DOI：
10.1038/oby.2009.296
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发表时间：
2010-03-01
期刊：
影响因子：
6.9
通讯作者：
Zeng, Qing
中科院分区：
文献类型：
--
作者：
Wang, Yonghong;Wang, Xiaolin;Zeng, Qing
本研究调查了重庆地区中国人群饥荒期间早期营养状况与成年期超重和肥胖风险之间的可能联系。体重、身高和BMI数据来自在公共卫生中心（我院）进行年度身体评估的人群（17，023）的记录。将1956-1964年出生的受试者分为三组：幼儿组，所有受试者在饥荒（1956-1958）前1-3年出生;妊娠组，在饥荒期间（1959-1961）出生;对照组，在饥荒之后（1962-1964）出生。与对照组相比，女性幼儿组和妊娠组的体重和BMI显著升高，而身高显著降低（P < 0.05）。女性超重的优势比在幼儿组（1.48倍，95%置信区间（CI）：1.288-1.689）比在妊娠组（1.26倍，95% CI：1.089-1.457）更明显。幼儿组女性肥胖的比值比（1.46倍，95%CI：1.288-1.689）显著高于对照组。对于雄性来说，饥荒对雄性成年体重没有任何影响。1959-1961年的大饥荒导致重庆市女性身高偏矮和体重偏胖，身高偏矮是重庆市BMI升高的危险因素。第二，饥荒似乎使重庆的雄性变得更矮更瘦。此外，饥荒期间幼儿和母亲的营养不良对健康状况产生了重要的后期影响。
This study investigated a possible association between early nutritional status during the famine, and the risk of overweight and obesity in adulthood in Chongqing Chinese population. The body weight, height, and BMI data were obtained from records of population (17,023) that had annual physical evaluations in the Public Health Center (in our hospital). Subjects born during 1956-1964 were divided into three groups: toddler group, all subjects who were born 1-3 years before the famine (1956-1958); gestational group, who were born during the famine period (1959-1961), and control group, who were born after the famine (1962-1964). The body weight and BMI were significantly higher, but the body height was significantly lower in the toddler and gestational groups (P < 0.05) in the female population as compared to the control group. The odds ratio of being overweight in females is more pronounced in the toddler group (1.48 times, 95% confidence interval (CI): 1.288-1.689) than in the gestational group (1.26 times, 95% CI: 1.089-1.457). The odds ratio of being obese in females is significantly higher in the toddler group (1.46 times, 95% CI: 1.288-1.689) than the control group. For males, the famine had no impact at all on the adulthood body weight in males. The Great Chinese Famine that affected the Chongqing population during 1959-1961 leads to shorter and overweight females, and the former is a risk factor for increased BMI in Chongqing. Second, the famine seems to be producing shorter but slimmer males in Chongqing. Furthermore, toddler's and maternal's malnutrition during the famine had important late consequences on the health status.