Haemodynamic contributions to post-exercise hypotension in young adults with hypertension and rapid resting heart rates.
Haemodynamic contributions to post-exercise hypotension in young adults with hypertension and rapid resting heart rates.
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血流动力学对患有高血压和快速静息心率的年轻人运动后低血压的影响。
DOI：
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发表时间：
1992
影响因子：
2.7
通讯作者：
J. Wesche
中科院分区：
文献类型：
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作者：
Floras Js;J. Wesche
本文测定了5例高血压和快速静息心率(临床心率>90次/min)青年患者的45min平板运动(以静息心率储备的70%)对血流动力学的影响，并与5例年龄匹配的正常血压者进行比较。运动后，高血压患者的血压降低，但血压正常的受试者没有。两组运动前平均心输出量相似，高血压组由运动前的6.8±-0.6降至运动后60min的5.4±0.6 L/min(P<0.0 1)。总的外周阻力在这个时候趋于更高。在血压正常的组中，这两个变量都不受先前运动的影响。高血压组运动前平均动脉压(-8.6+/-1.0vs-1.4+/-2.5 mm Hg；P<0.005.0 4)、心输出量(-1.4+/-0.3vs-0.1+/-0.1 L/分；P<0.0 5)和总外周阻力增加(+3.0+/-1.2vs 0.0+/-1.0Units；P<0.0 5)的降压作用更强。因此，在这组具有快速静息心率的年轻高血压受试者中，运动后低血压是由心输出量和每搏输出量的减少与血压下降不成比例调节的，这表明他们在急性运动后心功能持续受损。
The haemodynamic effects of 45 min of treadmill exercise (at 70% of resting heart rate reserve) were determined in 5 young adults with hypertension and rapid resting heart rates (greater than 90 beats/min in clinic) and were compared with those of 5 age-matched normotensive subjects. Blood pressure was lower after exercise in the hypertensive, but not the normotensive subjects. Mean cardiac output before exercise was similar in the two groups, and fell from 6.8 +/- 0.6 before to 5.4 +/- 0.6 l/min 60 min after exercise in the hypertensive group (P less than 0.01). Total peripheral resistance tended to be higher at this time. Neither variable was affected by prior exercise in the normotensive group. The depressor effects of prior exercise on mean arterial pressure (-8.6 +/- 1.0 vs. -1.4 +/- 2.5 mmHg; P less than 0.04) and cardiac output (-1.4 +/- 0.3 vs. -0.1 +/- 0.1 l/min; P less than 0.005) and the increase in total peripheral resistance (+3.0 +/- 1.2 vs. 0.0 +/- 1.0 Units; P less than 0.05) were greater in the hypertensive group. Thus, the post-exercise hypotension in this selected group of young hypertensive subjects with rapid resting heart rates was mediated by a decrease in cardiac output and stroke volume disproportionate to the fall in blood pressure, suggesting sustained compromise of their cardiac performance after acute exercise.